More articles about Cardiovascular Disease

Using data from the UK Biobank, researchers explored relative contributions that genetics and lifestyle make to cardiovascular disease and diabetes risk.

The project will focus on metabolic biomarkers that previous research has linked to heart disease, type 2 diabetes, and other common chronic diseases.

The effort will provide individuals with genetic testing to determine if they have the disorder, and when necessary,  with genetic testing counselling.

In a family with unusually low LDL cholesterol levels, researchers in China found a variant in the LIMA1 gene through exome sequencing.

Rainbow will offer Color's hereditary cancer and heart health genetic risk assessment tests to patients in Hong Kong.

Three microRNA that were significantly upregulated in plaques may serve as targets to affect cardiovascular disease development, according to a new study.

The study aims to understand the willingness of individuals with a clinical diagnosis of familial hypercholesterolemia and their family members to undergo confirmatory genetic testing.

Data from almost 19,500 individuals did not show clear ties between a heterozygous mutation in the HBB hemoglobin beta gene and ischemic stroke risk.

The prospective analysis suggests that the approach could help clinicians identify patients at risk of a stroke who could benefit from anticoagulant treatment.

Researchers saw clinically actionable heart disease mutations in fewer than 5 percent of sudden infant death syndrome cases interrogated by molecular autopsy.

Analyzing samples from Iceland and elsewhere, researchers uncovered one known and two new risk loci for aortic valve stenosis that are also associated with other heart risk pathways.

Using data for nearly 59,000 UK Biobank participants, researchers identified genes and pathways involved in heart rate variability, exercise response, and exercise recovery.

Detection of pathogenic or likely pathogenic variants implicated in cardiomyopathy declines in individuals with self-reported ancestry from under-studied populations.

Through a genome-wide association study and meta-analysis, researchers saw dozens of new and known blood pressure loci, including ancestry-specific associations.

Independent research teams identified mutations in a chloride ion channel gene in some cases of aldosteronism, a condition that can cause severe hypertension.

The polygenic score snags a greater percentage of people at risk of early heart attack than current tests that rely on single-gene variants or blood chemistry.

At the Precision Medicine World Conference, Invitae executives noted that early experience in the genetic screening pilot found more people received positive results than previously expected.

Investigators came up with a 182-variant risk score for early-onset coronary artery disease, which they tested on SNP data from UK Biobank participants with or without the condition.

With a two-stage atrial fibrillation GWAS, researchers took a crack at untangling the pathways, regulatory features, and tissue types contributing to the heart condition.

Using genetic risk scores, researchers uncovered apparent associations between abdominal aortic aneurysm and cholesterol or triglyceride levels.

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The New York Times and ProPublica say that many physicians fail to disclose their financial ties when publishing in medical journals.

The Wall Street Journal reports Human Longevity's valuation has dropped by 80 percent.

Science reports that the US National Cancer Institute is cutting its operating budget by 5 percent.

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.