A team of Austrian scientists used their new screening method to investigate genes and transcription factors regulating T cell receptor signaling.
The researchers will use single-cell genomics and other approaches to generate information that could ultimately be used to diagnose, monitor, and treat disease.
The funding will support research into the roles Alzheimer's disease-associated genetic variants play in neural cell biology.
A modified version of a commercially available magnetic bead cell sorting instrument from Miltenyi Biotec could be deployed to areas without cGMP facilities.
Cambridge Bioscience will exclusively distribute the Xcell platform in the UK and BioStream will disburse the system in Japan.
Researchers are making mutations in a cell's genome to mark it and later read out that information to create cell lineage maps and chemical interaction histories.
The partners will collaborate on pilot studies evaluating the Avatar system and analytics platform in the immunoprofiling of cancer patients.
Cell line engineers from Horizon Genomics said a method to make or undo fusion oncogenes in cell lines could help create reference standards for cancer diagnostics.
After CRISPR/Cas9 makes a double-strand break in DNA and the cell repairs it, the same set of mutations crop up again and again based on the genomic sequence.
The researchers plan to use their method to study neural transmission in disease and will also offer the technique as a service for other neuroscience labs.
A new study suggests CRISPR/Cas9-based gene activation can manipulate particular epigenomic patterns found in differentiated cells.
With an initial focus on exosome biology, the technology giant is looking for ways to use the microfluidic chip, which can sort particles as small as 20 nanometers.
A new study in Scientific Reports describes how scientists were able to replace an entire gene in a bacterial genome to study its function.
Considering the widespread use of the cell line, these findings could have significant implications for the research community.
By replacing amino acids during translation, scientists from several groups are homing in on a method to enable cell-specific proteomic analyses.
The firm will provide DNA from at least 50 mouse cell lines for use in a PCR-based validation assay.
A UK research team performed single-cell RNA sequencing on epiblast cells to learn more about how gene expression directs organ formation.
Two teams independently characterized Cpf1's on-target efficiency and off-target specificity, publishing their results last month.
Thermo Fisher will become the exclusive distributor for a technology to be developed with Boston-based Cytonome.
The agreement gives CRISPR Therapeutics access to a technology to create skeletal muscle stem cells for use in research on Duchenne Muscular Dystrophy.
While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.
Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.
In Nature this week: paternal age associated with de novo mutations in children, and more.
Nature News writes that researchers are still wrangling over the role of the p-value.