The researchers used DNA methylation profiles to define 82 central nervous system tumor classes, some of which differed from WHO tumor classes.
The Epigenetics For Female Personalised Cancer Care (EpiFemCare) project recently published its findings in two papers in the journal Genome Medicine.
The PCR-based methylation assay is intended to help predict the response of certain high-risk breast cancer patients to anthracycline-based chemotherapy.
Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.
The partners will perform blood-based tests on Oxford's Episwitch platform to monitor epigenetic changes of athletes with concussions.
In the long run, genome-wide DNA methylation profiling could be useful in diagnosing constitutional disorders as well as cancer.
The Jackson Laboratory scientists are aiming to create a molecular toolkit that allows for the precise and reversible manipulation of epigenetic modifications.
New studies suggest low-, intermediate-, and high-methylation subgroups exist in juvenile myelomonocytic leukemia, potentially offering insights into patient outcomes.
The funding will support research examining the epigenomic effects of social experiences and how they relate to health disparities.
The distribution agreement covers Zymo's nucleic acid products, including ones for DNA purification, RNA extraction, and microbiomic analysis.
The NIH has awarded $169 million this year to support 110 new projects in the Brain Research through Advancing Innovative Neurotechnologies Initiative.
The deal provides Precision for Medicine with a proprietary PCR-based technology that amplifies and detects euchromatic DNA expressed exclusively by cell types of interest.
Earlier this week, the company's scientific co-founders published an improved version of the ATAC-seq method that allows them to analyze frozen tissue.
The companies will integrate Cambridge's TrueMethyl technology for oxidative bisulfite sequencing with NuGen's sequencing library preparation kits.
Investigators identified dozens of neuronal subtypes in mouse and human brain samples using single-cell methylation sequencing, including a new neuronal subtype.
Participants tried to classify samples based on the epigenomic impact of cigarette smoke cessation and aerosol from modified- or reduced-risk products.
Five three-year awards, part of a larger $100 million commitment, were given to researchers working on epigenetics and the evolution of mobile genetic elements.
The company plans to use the funds to support expansion of its commercial footprint by increasing sales and marketing efforts and new technology development.
DNA methylation changes at two markers can differentiate anal cancer and high-grade anal intraepithelial neoplasms from low-grade and benign samples.
The technology is based on the work of UCLA's Steve Horvath, who has shown that DNA methylation age could predict all-cause mortality later in life.
British Nobel laureates and Fields Medal winners warn that a 'hard' Brexit could harm science across the UK, the Guardian reports.
Vox reports on inequities in genetic research and efforts to address them.
The New York Times reports that Arizona State University's Lawrence Krauss is retiring following allegations of sexual misconduct.
In PNAS this week: de novo NUS1 mutations linked to Parkinson's disease risk, candidate hepatocellular carcinoma drivers, and more.