Using the method, the researchers predicted the effects of over 140 million mutations in different tissues and identified mutations possibly associated with increased risk of several immune diseases.
With Pacific Biosciences sequencing, researchers found DNA N6-methyladenine modifications in the human genome and noted a role for it in tumorigenesis.
In an epigenome-wide association study of depression, the researchers tied DNA methylation to disease symptoms and suggested a role for axon guidance disruption.
Researchers examined DNA methylation and chromatin accessibility in preimplantation embryos using single-cell chromatin overall omic-scale landscape sequencing.
VolitonRx's research-use-only kits can be used to examine patterns in circulating nucleosomes in disease models, preclinical testing, and clinical trials.
Using a mass cytometry method called EpiTOF, researchers profiled histone modifications and variants in a range of immune cell types across individuals of different ages.
The PCR-based methylation assay is intended to help predict the response of certain high-risk breast cancer patients to anthracycline-based chemotherapy.
Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.
The Jackson Laboratory scientists are aiming to create a molecular toolkit that allows for the precise and reversible manipulation of epigenetic modifications.
New studies suggest low-, intermediate-, and high-methylation subgroups exist in juvenile myelomonocytic leukemia, potentially offering insights into patient outcomes.
The NIH has awarded $169 million this year to support 110 new projects in the Brain Research through Advancing Innovative Neurotechnologies Initiative.
A new study finds that the majority of patients at a Tijuana clinic received a diagnosis after first-line genome sequencing, the San Diego Union-Tribune reports.
In Genome Biology this week: post-transcriptional modification-based stratification of glioblastoma, single-cell analysis of gene expression and methylation in human iPSCs, and more.
