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The seven-year grant renews funding for the Antibacterial Resistance Leadership Group, led by Duke University and UCSF, with $15 million in 2020.
The researchers believe their findings could be used to change how patients' risk for breast cancer, colon cancer, or heart disease is calculated.
The new method, called sci-Plex, combines nuclear hashing and improved single-cell combinatorial indexing RNA-seq to profile the transcriptional response of single cells.
Researchers compared single-cell transcriptomic and epigenetic profiles of healthy blood cells and leukemia samples to find a role for RUNX1 in disease.
A regional court said certain 10x Genomics' products, including older GEM chips and some Chromium instruments, infringed a "utility model," similar to a patent.
Researchers found that about 12 percent to 15 percent of breast cancer patients carry multiple mutations in the gene, 95 percent of which are double mutations.
The company released data showing that its panel detects early-stage liver cancer with 71 percent sensitivity compared to 25 percent for the standard test.
This report contains a quantitative, evidence-based scoring framework to help guide the evaluation of constitutional CNVs across clinical labs.
A single-cell transcriptome study found increased numbers of cytotoxic CD4 T cells, which could be an adaptation to the later stages of aging.
The Chromium Connect, designed for pharma workflows and other high-volume customers, is one of several products coming out of 10x's R&D pipeline.
The system uses chemical epigenetic modifiers to activate the expression of target genes by recruiting an endogenous chromatin-activating machinery.
The company plans to market its GeoMx instruments for broader, more discovery-oriented research with a sequencing-based readout.
The firm reported that test volumes for its Cologuard colorectal cancer screening test rose 89 percent year over year.
The partners will integrate Genialis' gene expression analysis software with Thermo Fisher's Invitrogen Collibri Stranded RNA Library Prep kits.
MGI hopes to ship the sequencer, one of several products it unveiled at the International Conference on Genomics, to early-access partners in early 2020.
The company is hoping its technology can help predict which melanoma patients will respond to checkpoint inhibition using immune-related gene expression signals.
Visium, which provides gene expression information along with spatial information from the same tissue sample, will be shipped later next month.
A new study in Science used allele-specific expression data to find candidate genes that may have contributed to mendelian muscle disease in patients.
The researchers molecularly characterized cells found in cirrhotic tissue that express genes involved in pro-fibrogenic pathways that could be targeted by drugs.
The analysis further found that the degree of network perturbation correlated with the severity of toddlers' autism spectrum disorder.
Nearly 30,000 COVID-19 tests the UK sent to the US came back as void, according to the Telegraph.
Black principal investigators receive less favorable application scores when seeking US National Institutes of Health grants, the Chronicle of Higher Education reports.
New Scientist reports that both RNA and DNA may have been involved in the emergence of life on Earth.
In Nature this week: new Sperm-seq method enables crossover analysis, tumor-informed detection approach for minimal residual disease, and more.