The team found that a protein called OCT4 was necessary for the correct formation of a blastocyst in the first few days of embryonic development.
Investigators compared RNA sequence data in heart samples from individuals with dilated cardiomyopathy and samples from healthy transplant donor hearts.
Investigators used gene expression and immunological profiling to detect distinct immune responses in dengue virus-infected children with or without symptoms.
Research groups from the Broad Institute and the University of Washington have developed protocols to sequence RNA from large numbers of single nuclei and single cells.
The Washington State University and the University of Utah researchers said epigenetic variation may contribute to environmental adaptation in the birds.
Scientists at Duke University have found that a gene variant that affects cholesterol levels can potentially increase a patient's risk of contracting typhoid fever.
Researchers from Hong Kong imputed transcriptomes from GWAS data and compared them to drug-induced gene expression profiles.
The researchers observed that eliminating these microsatellite repeat expansion RNAs in patient cells reversed some hallmark features of the diseases.
NanoString Technologies this week provided investors with a mixed bag of news as it released its second quarter earnings and financial outlook for the rest of the year.
A new analysis hints that adenocarcinomas or squamous cell carcinomas may have certain overlapping expression patterns, regardless of the tissue of origin.
Ascendas will develop and commercialize molecular diagnostic systems and assays using certain of Fluidigm's microfluidic technologies.
Researchers developed a gene expression-based classifier for four gastric cancer subtypes and found that some are associated with better outcomes than others.
Examining more than half of its genome, researchers found the parasite's success is due to stripping its genome down to essential genes.
A Canadian research team has reported beta-blockers alter the gene expression changes that take place in a mouse model of heart failure.
New data now suggests that evaluating PD-L2 levels might better predict response to PD-1 targeting immune-oncology drugs than current tests that only measure PD-L1.
The companies will use ReadCoor's spatial omics platform to create a cell network map of the mouse brain to inform targeted drug delivery for Wave's medicines.
Paralogs may compensate for a mutated gene in tissues other than the disease-affected ones, researchers from Ben-Gurion University of the Negev in Israel found.
Israel-based BiomX uses a proprietary microbiome modulation technology to discover and develop microbiome-based therapeutics.
Revenue increased in all of the firm's sectors, driven by growth in the installed base for its nCounter systems, as well as increases in consumables sales.
A new TGen analysis has unraveled breast cancer mutational patterns specific to black women that could help improve outcomes and reduce recurrence.
A new study in JAMA finds that genetic tests might not be able to determine what diet is right for someone seeking to lose weight.
A genome-wide association study that linked common genetic variants to salivary gland carcinoma risk has been retracted, according to Retraction Watch.
Vampire bats' ability to live off blood is etched in their genomes and gut microbiomes, the Scientist reports.
In Genome Biology this week: peopling of the Sahara, epigenetic reprogramming analysis of liverwort, and more.