The firm is developing a biomarker panel to detect mutations in mesenchymal cells, with the goal of guiding drug treatment and improving earlier patient intervention.
The researchers identified genes that specifically extend the lifespan of neurons and found genes that increase the number of neurites in the brain.
Researchers compared gene expression patterns in the brains of people with and without schizophrenia to uncover differences in when genes were expressed.
Researchers generated a spatial transcriptome of mouse embryonic germ layer tissues from the pre-gastrulation stage to the late gastrulation stage.
The method allows for the annotation of cells by their genotype and capture of single-cell transcriptomes, even when the cells aren't morphologically distinct.
Through a transcriptomic analysis, the researchers developed a catalog of gene expression with the olfactory mucosa of half a dozen mammals.
A team led by researchers at the University of Maryland uncovered thousands of gene pairs whose expression levels affect cancer survival and drug response.
Researchers analyzed RNA sequencing data gathered from induced pluripotent stem cells as they differentiated into heart muscle cells.
At the WIN Symposium, a researcher from Sheba Medical Center discussed ongoing efforts to develop a 22-gene signature for predicting brain metastasis in NSCLC.
APEX-seq builds on a proteomic labelling technique and offers a new spatial genomics tool for looking at the life of transcripts within the cell.
So-called DNA microscopy is the latest entrant to the rapidly growing spatial genomics field that combines molecular analysis with imaging.
The Singapore-based firm plans to use its single-cell RNA and protein assay to help optimize the production of CAR T cells and guide their use in patients.
In patients with a range of rare diseases, RNA sequencing in blood had a 7.5 percent diagnostic rate and identified candidate genes in 16.7 percent of cases.
The team evaluated various technologies in an attempt to develop a framework to compare future methods against and to serve as a guide for researchers.
The deals with Covance, NeoGenomics Laboratories, and Navigate BioPharma Services aim to expand access to NanoString's PanCancer IO 360 Gene Expression Panel.
The actual match rate is significantly higher than the 10 percent rate the researchers anticipated they would see when the study began in 2017.
The company is seeing increasing interest in its GeoMx platform with numerous studies from early users presented last month at AACR.
New methods for spatial transcriptomic profiling include a sequential FISH-based method and one that makes use of DNA-barcoded bead arrays.
Researchers built a single-cell gene expression atlas of premalignant lesions and early gastric cancer to find shifts that could portend disease progression.
The Massachusetts Institute of Technology-led team uncovered cell-type-specific transcriptional changes that occur early on in disease development.
Stephen Hahn, the nominee to lead the US Food and Drug Administration, underwent a Senate confirmation hearing yesterday, the Washington Post reports.
The US Food and Drug Administration has approved an RNA interference drug to treat acute hepatic porphyria.
Gizmodo looks over the past decade of consumer DNA testing to find the field to be lacking.
In Nature this week: native RNA sequencing and analysis of a human poly(A) transcriptome, nanopore sequencing-based method to analyze short tandem repeat expansions, and more.