From single-cell RNA sequence data on neurogenic brain samples from young and old mice, researchers saw T cell activity that seems to staunch neural stem cell proliferation.
The firm plans to address the fact that only 2 percent of human DNA samples used in pharmaceutical research are from Africans or those of African ancestry.
Nuclear and mitochondrial genome sequences from 120,000-year-old Neanderthal remains from Germany and Belgium revealed genetic ties to more recent Neanderthal populations.
The new initiative, called MEGA+, will extend the process of genomic data sharing to all medical data, including electronic health records and imaging files.
The researchers found that dark regions impact more than 700 protein-coding genes and also identified a novel mutation in a known Alzheimer's disease gene.
Genome-wide association analyses spanning 26 phenotypes in diverse populations revealed new risk variants and population-specific contributions for known SNPs.
The San Diego-based firm emerged from stealth mode with a plan to develop technologies to improve the quality and reduce the cost of genetic analysis.
Scientists from the UK and China discussed two new NIPTs that include single-gene disorders and a study to estimate disease recurrence risk in families.
The Genes for Good Project has engaged 80,000 Facebook users via its online application and genotyped 27,000 people to date.
Regeneron is covering the cost of the sequencing and genotyping, and both partners will have access to the data for research purposes.
Harvard and Brigham and Women's Hospital researchers will help guide Sanford in using and interpreting data collected through its Sanford Chip pharmacogenomic test.
Consenting participants will have their deidentified sequence data used for research and will also have the chance to learn if they have clinically actionable results.
The partners are both "investing heavily" in the study and will have access to the data and to new technologies and interventions.
NatGeo will continue to conduct research using its database, which includes data on roughly a million individuals.
The trials are part of the second phase of the Implementing Genomics in Practice program, which is slated to receive $42 million in funding over 5 years.
A study of more than 10,000 women showed cancer predisposition genes confer similar risks of breast cancer in African-American women as in whites.
The project, established by the National Cancer Center of Japan, screens target genes in lung cancer to advance the development of new drugs and diagnostics.
Tissue-agnostic drug development approaches have their own set of scientific and financial considerations, but some drugmakers are taking on those challenges.
The FLASH method, which depletes unwanted DNA from samples, allows labs to perform deep metagenomic sequencing on smaller, less expensive instruments.
The researchers traced the timing of when these clusters developed to the emergence of agriculture in three river valleys.
Holden Thorp is to be the new editor-in-chief of Science and its related journals.
A genetic analysis of salmon scales collected over the course of a century points to a sharp decline in the number of fish returning each year to river in British Columbia, CBC reports.
Adelaide University has suspended the head of an ancient DNA lab as its investigation of workplace bullying continues, Australia's ABC News reports.
In PNAS this week: gene expression profiles of adipocyte subtypes, computational approach for improving plant expressome analysis, and more.