By using array-synthesized guide-donor oligonucleotide pairs, the team's gene editing technique allows accurate and detectable phenotyping in yeast cells.
Through a meta-analysis of nearly 140,000 people, an international team of researchers tied 112 loci to increased intraocular pressure, a glaucoma risk factor.
The researchers said the pattern of genetic changes accompanying cultural shifts in Southeast Asia resembles what has been found in Europe.
The study aims to understand the willingness of individuals with a clinical diagnosis of familial hypercholesterolemia and their family members to undergo confirmatory genetic testing.
Researchers described diet-related patterns of gut microbial diversity, microbiome ties to psychiatric disease, and more.
Genome-wide association study hits can uncover potential therapies for conditions like inflammatory bowel disease, a Biology of Genomes speaker said.
The company anticipates 2018 revenues in the range of €11 million to €12 million, excluding the impact of recently acquired TGR Biosciences.
Baylor College of Medicine's Olga Dudchenko sad the approach could assemble de novo mammalian genomes for less than $1,000.
An international team found that survival estimates differed significantly between patients with germline mutations in different medulloblastoma predisposition genes.
Working independently, two research teams have combined CRISPR-based targeting and APEX labeling to identify proteins linked to specific portions of the genome.
In a talk at the meeting, Riken's Piero Carninci described the RADICL-seq tool he and his colleagues developed.
Using genome sequences for hundreds of ancient individuals, researchers have analyzed population dynamics and displacements around the Eurasian steppe.
Stanford University's Eilon Sharon used CRISPeY to conduct a genome-wide precise editing study to study the fitness consequences of variants found in different yeast strains.
Researchers used UK Biobank data to uncover genetic loci — many linked to pigmentation processes, but also novel ones — associated with being able to tan.
The funding will support the university's MRC Human Genetics Unit, which is investigating the genetic underpinnings of human health and disease.
Researchers identified trait-related variants by sequencing more than 400 upland cotton accessions and nearly 250 representatives from two diploid Gossypium species.
Along with a polygenic risk score enhanced in migraine sufferers, new research reveals a high-frequency variant implicated in cold adaptation and migraine in Europeans.
A team of European researchers analyzed DNA from infected medieval skeletons to find the HLA allele DRB1*15:01 was more common among leprosy patients.
Ahead of the national launch, 44,000 early participants signed up for the program during a beta phase, and 26,000 people have completed the enrollment process.
The effort aims to sequence at least 150 animals, plants, and microbes selected for their potential benefits to Canada in the next three years.
Lawmakers have asked four direct-to-consumer genetic testing companies to explain their privacy policies and security measures, according to Stat News.
The Trump Administration has proposed a plan to reorganize the federal government, the Washington Post reports.
In Science this week: genetic overlap among many psychiatric disorders, and more.
The Economist writes that an increasing number of scientific journals don't do peer review.