More articles about Gene Silencing/Gene Editing

After acquiring Dharmacon, as well as licensing a wide array of editing technologies, Horizon has built itself into a repository of knowledge and tools.

Investigators from the school will use the funding to continue a research program applying genomics to hearing loss screening and treatment.

The company uses genome editing technologies for agricultural and biomedical applications, including therapeutic cell, tissue, and organ generation.

The automated, whole-genome directional genomic hybridization system can measure de novo random, low-frequency, and complex structural variations.

The Suzhou, China-based company is developing medicines and molecular diagnostics based on its gene editing and delivery technologies.

The researchers showed that Cas12a discriminates strongly against mismatches to DNA targets, leading to less off-target DNA cleavage than with Cas9.

The system, called EvolvR, can continuously diversify all nucleotides within a tunable window at user-defined loci using CRISPR-guided nickases.

The teams, from the Chinese Academy of Sciences and NYU Langone Health, generated viable yeast strains with just one or two chromosomes.

The firm said it will use the funds to build its IP portfolio, expand its team, and develop an infrastructure for partners to build on its CRISPR platform.

The NIH is providing the money under a recently launched initiative to advance genome editing in humans, with an eye toward therapeutic applications.

The researchers said their method for mapping genetic interactions can serve as a blueprint for mapping the genetic landscape of human cells.

The firm's CEO Kevin Ness said confirmation of MAD7's editing activity in human HEK293T cells shows the potential for Inscripta's technology.

Locus said it will pair the EpiBiome platform with its own CRISPR-based synthetic biology system to develop products that can edit the microbiome.

Wellcome Sanger Institute researchers showed that Cas9-induced DNA breaks frequently resolved into deletions extending over many kilobases in the genome.

Researchers in the UK developed heritable Cas9-mediated mammalian genome editing that is acutely controlled by a cheap lysine derivative.

The Somatic Cell Genome Editing program was established earlier this year to help remove barriers from the adoption of genome editing for treating patients.

In exchange, Editas has the exclusive right to be the first to negotiate for licenses to genome-editing inventions that arise from the sponsored research.

The approach generates a gRNA against a common genetic element called the flippase recognition target, making genome editing faster and scarless in E. coli.

By combining iPSCs, CRISPR gene editing, and transcriptomic approaches, researchers examined the effects of an Alzheimer's disease risk variant on brain cells.

The NMI Natural and Medical Sciences Institute at the university and its affiliate will use the patents to expand their cell-based research service offerings.

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Though many details have yet to be worked out, the draft deal for the UK's withdrawal from the EU is giving researchers some hints for what they can expect, Nature News says.

DNA testing has solved a 100-year-old mystery contained in the skull and teeth samples of a now-extinct monkey that once inhabited Jamaica, Gizmodo reports.

As the UN ponders a ban on gene drives, one malaria researcher says there are less dramatic ways to fight the disease in Africa than unleashing GM mosquitoes on a whole continent.

In Nature this week: an improved reference genome of the Aedes aegypti mosquito, genomes of four species of truffles, and more.