More articles about Gene Silencing/Gene Editing

The NIH is providing the money under a recently launched initiative to advance genome editing in humans, with an eye toward therapeutic applications.

Cigna began covering the company's ThyGeNext next-generation sequencing-based test for thyroid cancer risk assessment in 2017.

The researchers said their method for mapping genetic interactions can serve as a blueprint for mapping the genetic landscape of human cells.

The firm's CEO Kevin Ness said confirmation of MAD7's editing activity in human HEK293T cells shows the potential for Inscripta's technology.

Locus said it will pair the EpiBiome platform with its own CRISPR-based synthetic biology system to develop products that can edit the microbiome.

Wellcome Sanger Institute researchers showed that Cas9-induced DNA breaks frequently resolved into deletions extending over many kilobases in the genome.

Researchers in the UK developed heritable Cas9-mediated mammalian genome editing that is acutely controlled by a cheap lysine derivative.

The Somatic Cell Genome Editing program was established earlier this year to help remove barriers from the adoption of genome editing for treating patients.

In exchange, Editas has the exclusive right to be the first to negotiate for licenses to genome-editing inventions that arise from the sponsored research.

The approach generates a gRNA against a common genetic element called the flippase recognition target, making genome editing faster and scarless in E. coli.

By combining iPSCs, CRISPR gene editing, and transcriptomic approaches, researchers examined the effects of an Alzheimer's disease risk variant on brain cells.

The NMI Natural and Medical Sciences Institute at the university and its affiliate will use the patents to expand their cell-based research service offerings.

By using array-synthesized guide-donor oligonucleotide pairs, the team's gene editing technique allows accurate and detectable phenotyping in yeast cells.

The company — which was cofounded by David Liu, Feng Zhang, and Keith Joung — has licensed base editing technology from Harvard and the Broad Institute.

A panel at the Biology of Genomes meeting discussed the ethical, legal, and social ramifications of germline gene editing.

Researchers used CRISPR-Cas9 screening assays in mouse and human cells to track down point mutations in the PARP1 gene that boost resistance to PARP inhibitor drugs.

The technology behind Mammoth's platform bears a striking resemblance to the CRISPR-based SHERLOCK platform developed by researchers at the Broad Institute.

In a note to investors, Cowen analyst Doug Schenkel called the decision "odd," and wondered if there would be more to come.

Stanford University's Eilon Sharon used CRISPeY to conduct a genome-wide precise editing study to study the fitness consequences of variants found in different yeast strains.

The company said its product revenues for the year rose 101 percent while its services revenues rose 7 percent.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.