The partners' first project will involve using Cellectis' TALEN gene editing technology to create virus-resistant human cells.
The team paired the SHERLOCK platform developed in Feng Zhang's lab with a protocol that detects viruses directly from bodily fluids in less than two hours.
The company said it plans to develop a CRISPR-enabled platform capable of detecting any biomarker or disease containing DNA or RNA.
The technology is designed to enable more efficient targeted DNA cassette insertion in the engineering of animal models.
The team searched for coding and noncoding elements involved in acquired resistance to cytarabine, the main treatment for acute myeloid leukemia.
The team's approach discovered cell-essential and human embryonic stem cell-essential genes in karyotypically stable human pluripotent stem cells
The researchers have made the pipeline, called CRISPRdisco, free for other scientists to use through Github, and are hoping the community will also help refine and update it.
The team unexpectedly found that some supposedly essential yeast genes are dispensable, and that other essential genes have large dispensable regions.
South Korea-based Macrogen has acquired a a non-exclusive research tool license to CRISPR-Cas9 technology.
Element Genomics' technology will increase UCB's pipeline, focusing on target discovery and interpretation in disease relevant systems.
The team integrated tumor barcoding, genome editing, and ultra-deep barcode sequencing to interrogate pairwise combinations of tumor suppressor alterations.
One team suggested Cas4 is required to assist the Cas1-2 complex, while the other said Cas4 helps maintain fidelity during CRISPR adaptation.
The startup was cofounded by the Broad Institute's Feng Zhang and Harvard's David Walt among others, and raised $15.6 million in June.
A Chinese Academy of Sciences-led team noted expansions within the gene families of olfactory, gustatory, and other receptors in the insect.
Pairwise, an agricultural startup using gene editing to address global food challenges, was cofounded by Feng Zhang, David Liu, and Keith Joung.
The latest version of the nucleic acid detection platform uses three CRISPR enzymes, making it more sensitive and capable of smaller quantitative measurements.
Inscripta is creating its own market and customer base while also utilizing the expertise of its customers to refine and improve its products.
The xCas9 variant developed by David Liu and his colleagues recognizes a broad range of PAM sequences and has greater DNA specificity than spCas9.
By switching off tumor suppressor genes in immunocompetent mice, the team saw that liver cancer developed and killed the mice within four to five months.
The firm said it will use the funding to expand its research capabilities, including the continued development of the MADzyme family of CRISPR enzymes.
Sometimes genetic tests give inconclusive results and provide little reassurance to patients, the Associated Press reports.
Vox wonders whether gene-editing crops will be viewed similarly as genetically modified organisms of if people will give them a try.
In Science this week: research regulation and reporting requirement reform, and more.
With H3Africa, Charles Rotimi has been working to bolster the representation of African participants and African researchers in genomics, Newsweek reports.