The team's Pro-Code system enabled simultaneous high-dimensional protein-level phenotyping of hundreds of genes with single-cell resolution.
The researchers used the platform, named CRISPR-GO, to study how spatial organization of the genome in the nucleus governs cellular function.
GenAhead said it will use the IP it had licensed from ERS for genome editing applications in pharmaceutical drug discovery and development.
A team led by Walter and Eliza Hall Institute researchers found that ovarian tumors with complete BRCA1 methylation and silencing were more susceptible to treatment.
For the first time, researchers used mitochondrially targeted zinc-finger nucleases to induce specific elimination of mutant mtDNA across the heart.
The researchers were able to measure the fitness effects of thousands of natural genetic variants in yeast at single-base resolution.
Under the terms of the agreements, Thermo Fisher obtains global non-exclusive rights to products, tools, and research services involving the technologies.
The firm said it saw a robust contribution in the first half of the year from its Dharmacon business and noted that it increased its reach into the US market.
The international team then used the approach to show that appropriate guide RNA design can reduce off-target effects of editing in mouse livers.
The researchers said their findings could help classify BRCA1 variants, particularly one whose impact on cancer risk is currently not clear.
A new study shows that DNA targets bound by nucleosomes are cleaved less efficiently than targets lacking nucleosomes, which could inform target selection.
The court upheld a judgement of no interference-in-fact from the Patent Trial and Appeal Board, leaving the Broad in control of key CRISPR IP.
The researchers are studying the molecular links between bile duct cancer and liver fluke infection, and testing a vaccine to protect against infection.
These Cas inhibitors — published in two studies — inhibit the activity of several Type V-A and Type I-C CRISPR systems, including several Cas12a orthologs.
Solana, founded in 2017 by former Illumina employees, has launched hundreds of products, including DNA sequencing solutions.
After acquiring Dharmacon, as well as licensing a wide array of editing technologies, Horizon has built itself into a repository of knowledge and tools.
Investigators from the school will use the funding to continue a research program applying genomics to hearing loss screening and treatment.
The company uses genome editing technologies for agricultural and biomedical applications, including therapeutic cell, tissue, and organ generation.
The automated, whole-genome directional genomic hybridization system can measure de novo random, low-frequency, and complex structural variations.
The Suzhou, China-based company is developing medicines and molecular diagnostics based on its gene editing and delivery technologies.
Researchers are refining a tool to predict a woman's risk of developing breast cancer, according to the Guardian.
According to Stat News, the partial government shutdown in the US could soon affect the ability of the Food and Drug Administration to review new drugs.
In PNAS this week: gypsy moth genome sequenced, phylogenomic analysis of Polyneopterans, and more.
CNN reports that people's genes tend to have a greater influence on their risk of developing disease than their environment, but it varies by phenotype.