As part of the deal, Heidelberg, Germany-based Febit will install several of Life Tech's SOLiDs and real-time PCR systems in its genomic-services facility, and aims to process around 1,000 samples per week by the first half of next year.
The agreement, under which Life Technologies will co-market Agilent's SureSelect Target Enrichment System with the Applied Biosystems SOLiD sequencer, follows a similar deal that Agilent signed with Illumina in April.
The method, called primer extension capture, or PEC, is especially suited for capturing short DNA fragments in order to sequence a few small genomic regions in large numbers of individuals. Originally developed to analyze areas of interest in the Neandertal nuclear genome, it might also be useful for other types of targeted sequencing applications.
This summer, Agilent plans to introduce a SureSelect kit for paired-end sequencing on the Illumina GA. The company is also working on versions of SureSelect for use with Applied Biosystems' SOLiD sequencer and the 454 Life Sciences platform.
Over the next year or so, Polonator developers plan additional improvements, including reagent kits, increased read lengths, and a simpler library preparation protocol. By 2010, they expect the output per run to increase tenfold, to 100 gigabases.
Life Technologies, J. Craig Venter Institute, BioNanomatrix, Nanosys, Geospiza, HDF Group, Pressure BioSciences, Cofactor Genomics, Ambry Genetics, Affymetrix, Navigenics, Enzymatics, New York State Department of Health, University of Washington