The startup plans to use the funds to scale its single-cell DNA analysis technology for blood-based cancer research and expand into CRISPR applications.
The method, called negative enrichment, protects DNA regions of interest prior to degrading the surrounding DNA, making the target fragments easier to read.
The life science research tools firm is offering 8,150,000 shares of its common stock at a price of $6.75 per share for gross proceeds of about $55 million.
The collaboration will use 1CellBio's InDrop system to examine inflammatory and immunological conditions in patients and develop disease profiles.
For a study published in Molecular Cell this month, researchers at Tsinghua University tested and compared three droplet-based single-cell RNA sequencing methods.
Bioké will distribute Ireland-based Syntec's Medimachine semi-automated homogenizer products in the Netherlands, Belgium, and Luxembourg.
The UCSD spinout has developed a modified version of the Hi-C protocol to capture chromatin conformation that uses multiple restriction enzymes.
The firm believes its Parsortix cell separation system, so far used for oncology, can extract rare fetal cells from maternal blood to detect genetic disorders.
The company said that future health tests it might launch in its store may require features that are only available on version 2 of the Exome+ test.
CoPrimers use a proprietary chemistry that attaches primers to probes with a polyethylene glycol-based linker, which prevents the formation of primer-dimers.
At the ICG-13 conference, BGI previewed a high-throughput sequencer, MGISEQ-T7, that will be commercially available in 2019 and have a throughput of up to 20,000 genomes per year.
The platform uses a gravity-based method to capture and isolate up to 100,000 individual cells per run, while maintaining viability and structural integrity.
The company plans to use the technology, originally developed by Good Start Genetics, to offer sample preparation solutions and data analysis for NGS.
Biomatrica's sample collection tubes ensure quality preservation of circulating tumor DNA and cells, promoting high-quality liquid biopsy results, Exact said.
Teleflex will use Arcis' nucleic acid sample preparation chemistry to develop a rapid diagnostic assay based on RNA detection.
The new RNA sequencing analysis workflow integrates Roche's RNA-seq library kits with Genialis' automated data processing pipeline for gene expression analyses.
The UK-based nucleic acid sample prep solutions provider will use the funds to accelerate product development and company growth.
The firm has been piecing together a collection of acquisitions over recent years that expand its presence in the genomics market, particularly custom oligos.
LGC said that the acquisition will increase its presence in the nucleic acid market, in addition to its previous acquisitions in the last few years.
The firm aims to launch the new assay in the first quarter of next year and plans to develop other products for single-cell sequencing library prep.
NPR reports that researchers in Italy are testing a gene drive aimed at controlling mosquito populations.
Researchers may experience the effects of the government shutdown for a while, the Los Angeles Times reports.
A new study finds that the majority of patients at a Tijuana clinic received a diagnosis after first-line genome sequencing, the San Diego Union-Tribune reports.
In Genome Biology this week: post-transcriptional modification-based stratification of glioblastoma, single-cell analysis of gene expression and methylation in human iPSCs, and more.