The technique is based on a MALDI triple-quadrupole platform and exploits the selective multiple-reaction monitoring transition features of the instrument to circumvent problems resulting from interference that can plague existing methods.
More than a year after a project to map out the human proteome was first proposed, members of the Human Proteome Project and attendees of HUPO's annual conference revisited the merits, challenges, and advisability of such a project.
Clinical proteomics may have a spotty and troubled history, but at the Human Proteome Organization's annual conference in Toronto, the push to move proteomics from the research lab to the clinical setting was everywhere to be seen.
Few in proteomics had probably ever heard of Danaher until two weeks ago. But the once-struggling real estate investment trust has been transformed by the Rales brothers into a successful global conglomerate, and by the end of the year is poised to become the top mass-spec firm in the world with the purchase of the ABI/MDS joint venture.
Omic is the second spinout formed by UMBI in as many months, even as the institute, which is part of the University System of Maryland, is currently transitioning various components of its operations to other UM campuses in a bid to maximize research collaborations and boost external funding.
Danaher will spend $1.1 billion to acquire the mass spec joint venture of MDS and Life Technologies, as well as the Molecular Devices business owned by MDS. It expects those businesses to add $650 million in annual revenues to its life sciences segment.
Boston University School of Medicine researcher Catherine Costello plans to add a Bruker solariX system to the institute's mass spec resource and also will collaborate with the company to develop new glycomics and proteomics-related mass spec approaches.
Researchers in the Netherlands have identified 44 protein biomarkers that appear repeatedly in 2D gel electrophoresis-based disease biomarker studies and have linked them to cellular stress response, adding "in future proteomic studies, more profound approaches should be applied to look beyond these proteins to find specific biomarkers."
The survey conducted by Leerink Swann found that 31 percent of university-based researchers consider capital-equipment purchases their top budget priority, and within that group, 35 percent cited mass specs as their single biggest priority.