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Researchers measured proteins produced by 193 deletions in 136 CRISPR-deleted genes and found residual protein expression in roughly one-third of these cases.

The companies plan to explore opportunities to use Thermo Fisher's LC-MS instrumentation to develop tools to determine the risk for adverse pregnancy outcomes.

The company delivered organic growth across its four business segments and raised its revenue and earnings guidance for the year.

The study is one of several recent efforts to detect bacteria directly with mass spec, which could eliminate the need for culturing and speed turnaround time.

While the approach lost some of its luster after failing to deliver on early hype, technological improvements are revitalizing interest among researchers.

The method could prove useful both for studying tumor immunology and in the development of cancer immunotherapies, said one of the researchers.

The partners will more thoroughly connect Protein Metrics' software suite and Sciex's high-resolution accurate mass (HRAM) spectrometry systems.

Gathering last week in Australia, the community continued its years-long push towards increased clinical relevance and integration with other omics disciplines.

The instrument's ability to run in negative-ion mode allows it to move beyond its traditional focus on proteins and into the analysis of other analyte classes.

Under the agreement, the companies plan to offer combined genetic and biochemical testing services out of Blueprint's clinical laboratory in Seattle.

The approach uses miniaturized sample prep and isobaric tagging and can identify up to 2,300 proteins in single cells and analyze around 100 cells per day.

Under the deal, Mobilion is implementing its SLIM ion mobility technology on Agilent's QTOF mass specs, with a broad commercial launch planned for 2021.

The South San Francisco, California cellular analysis firm alleges IonPath has infringed two patents and has been intereferening in its contracts.

Developed using the center's "industrialized" proteomics workflow, the panel identified patients up to a year before their diagnosis with 89 percent accuracy.

The partners plan to develop a number of liquid chromatography mass spectrometry methods for clinical research applications.

More powerful and user-friendly mass spec systems could drive an uptick in interest in the technique, suggested a leading top-down researcher.

The Tokyo-based firm said it will use the funding to support prototyping and commercialization of its mass spectrometry and optical spectroscopy instruments.

The study authors said that the technique could help researchers better prioritize which of the vast number of protein PTMs to investigate more thoroughly.

The company reported revenues of $490.2 million, up from $443.7 million in Q2 2018 and beating the consensus Wall Street estimate of $477.8 million.

The company's Q2 revenues were up less than 1 percent from $596.2 million in Q2 2018, and short of the average Wall Street estimate of $601.4 million.

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Nature News reports that recent proposed changes to the US National Science Foundation have raised concerns about a shift away from the agency's focus on basic research.

Noel Rose, the "father of autoimmunity," has died at 92, the Washington Post reports.

According to CNN, Legionella was discovered in buildings leased by the Centers for Disease Control and Prevention as they reopened following coronavirus pandemic-related closures.

In PLOS this week: genetic analysis of malaria parasite populations in Southeast Asia, genomic surveillance of yellow fever virus in São Paulo, and more.