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In a revised remedies proposal to the UK's Competition and Markets Authority, Illumina offered licenses to a wider swath of IP held by it and PacBio.

Using RNA sequencing, researchers profiled gene expression patterns in cutaneous leishmaniasis lesions, identifying a handful of genes with treatment-associated expression.

The Redwood, California-based company plans to use the funding to drive the commercial launch of its semiconductor chip-based sequencing-by-synthesis instrument.

The funding will be used to adapt the company's web-based genomic data analysis methods platform for computational analyses developed for ENCODE.

The Series A financing will go toward expanding access to its liquid biopsy-based test to more patients in Asia and North America, it said.

Recent studies question the clinical utility of tumor mutational burden as a biomarker for immuno-oncology response, and the FDA clearance includes no therapeutic indications.

The firm also recently released the results of collaborations with Admera Health and RareCyte that used its multiplex PCR-based target enrichment technology.

The partners plan to employ Personalis' ImmunoID NeXT platform to investigate biomarkers of response and mechanisms of resistance to cancer therapies.

Clinical genomics is just one business area for PHIX, which also intends to sell genomic tools and introduce a variety of agriculture and lifestyle-focused tests.

PTC Therapeutics is developing a gene therapy for the rare genetic disease AADC deficiency, which impacts the production of two key neurotransmitters.

The company is hoping that the comprehensive solution will help bring on more pharma customers and offer extended opportunities for current users.

Mitochondrial sequences suggest some haplogroups found in Finland today arrived in the region pre-Iron Age, though population distributions have shifted.

Medley Genomics' software, called HotNet2, assesses tumor genomic heterogeneity from large-scale sequencing datasets across patient cohorts.

The trial aims to combine personal information, pharmacogenomics data, and machine-learning tools to select the best anti-seizure medication for patients. 

 

 

Sequencing and other experiments on barcoded Plasmodium berghei mutant strains helped researchers narrow in on key metabolic pathways in the parasite's liver stage.

The genetic testing firm is offering approximately 2.3 million shares at $11.25 per share and plans to use the funds for general corporate purposes.

The German molecular diagnostics firm is preparing for its merger with US-based OpGen, which is slated to close in the first quarter of next year.

The company attributed much of the increase to its work with the VA’s Million Veteran Program, which made up three quarters of its earnings in the quarter.

In a response to the UK CMA's findings that the PacBio deal would lessen competition, Illumina said it would be open to licensing some IP to Oxford Nanopore.

Under a collaboration agreement, the firms plan to put together Agilent's SLIMS laboratory information system and MGI's DNBSeq series of sequencing platforms.

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Researchers are sampling the wild relatives of modern crops to try to preserve genetic diversity, NPR reports.

MIT's Search for Extraterrestrial Genomes is developing sequencing tools to use to try to detect whether there is any life on Mars, Quartz reports.

Undark reports on a bill introduced this year to the US House of Representatives to strengthen scientific integrity.

In Genome Research this week: post-zygotic mutations in diabetes development, single-cell RNA sequencing study of aging, and more.