Life Tech's sample prep and PCR products for H1N1 testing contributed approximately $15 million in revenue for the fourth quarter and about $45 million for the full year. The company also saw "continued strength in the TaqMan array business, in addition to strong demand for qPCR instrumentation and reagents."
Millipore claims that its test, which incorporates transcription-mediated amplification technology developed by Gen-Probe offshoot Roka Bioscience, provides a few advantages over PCR-based Mycoplasma testing.
The key to the system is helicase-dependent amplification — an isothermal amplification method that is similar to PCR in many ways but does not require a thermal cycler and is therefore more suitable for in-field use.
Investigators will compare results from the FilmArray PCR test to results from conventional platforms, like viral culture and antibody tests, as well as to results from other molecular diagnostic technologies.
The products, which join a line of TaqMan assays for mature microRNAs that Applied Biosystems launched in 2005, are intended to solidify the company's position in the highly competitive RNA research market.
In a new paper, Polyplus-transfection scientists showed that the company's zipped nucleic acids work as hydrolysis probes in quantitative PCR, adding to previous work that demonstrated their use as primers.