The clearance enables 23andMe to report on the two most common variations in the MUTYH gene influencing MAP, which increases risk of CRC development.
One locus appears to be more common among individuals with Native American or East Asian ancestry and suggests there was convergent evolution of skin color among Eurasians.
A number of the genes implicated are also the targets of approved therapeutics or of ones under testing.
Researchers were able to classify 1,244 of 4,585 putatively clinically relevant rare variants genotyped on the UKB microarray as high quality.
Results from two GWAS studies suggest that 15-LO inhibitors could be a viable treatment for nasal polyps and chronic rhinosinusitis.
Researchers uncovered nearly a hundred loci to general risk tolerance and hundreds more to particular risky behaviors.
Lineagen hopes to use PWNHealth's consumer-oriented model to expand access to its testing services for developmental delay and autism spectrum disorder.
Arbor Biosciences' portfolio includes custom DNA microarrays and oligonucleotide libraries, as well as a line of targeted sequencing panels.
With ever more data in hand, providers are seeking to enhance their services, providing more detailed ancestry estimates while introducing new offerings around genetic traits and health.
An array-based analysis involving more than two dozen patients led to a miRNA signature associated with overall survival in primary central nervous system lymphoma.
The firm's fourth quarter preliminary revenues increased by 11 percent to $865 million year over year, while full-year revenues jumped by 21 percent to $3.3 billion.
Further analysis linked the new loci to genes implicated in immune-related tissues and cell types, as well as to lipid-related processes, suggesting their involvement in disease development
The test combines qPCR and microarray technology to detect carbapenemase-producing enterobacteriaceae, a bacteria resistance to carbapenem antibiotics.
The firm reported that it expects product and service revenue of approximately $23.5 million for the fourth quarter of last year and $83.5 million for full-year 2018.
Upon clearance of the platform, the company will commercialize the TruDiagnosis, an IVD system for genotyping multiple genes in a DNA sample, this year.
A GWAS meta-analysis involving 10,074 PCOS cases revealed three new and 11 known risk loci, along with a relatively consistent genetic architecture among cases.
While canine genetic testing providers bemoan a lack of quality standards, they disagree on what specific rules labs should follow.
The government has also pledged €5 million from the European Regional Development Fund to support the integration of genetic data into routine medical care.
Researchers have identified promising polygenic risk scores for estimating overall breast cancer risk as well as estrogen receptor-positive forms of disease.
The researchers generated a skull shape score and applied it to a European ancestry cohort to tease out introgressed Neanderthal DNA linked to head shape.
23andMe has a holiday popup shop at a mall and could open additional stores, Bloomberg reports.
By studying koalas and a retrovirus that infects them, researchers may have uncovered a new sort of 'immune response' that occurs at the genomic level, Agence France Presse reports.
NPR reports that the first person in the US given a gene editing-based therapy for a genetic disorder is heading home.
In Science this week: ancient genomes reveal social inequality within individual households, new method for quantifying genetic variation in gene dosage, and more.