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Zeiss, Columbia U, MDCC, OmniGene Bioproducts Among Patent Winners

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Carl Zeiss has been awarded US Patent No. 6,823,079, “Device for examining samples.”

Inventors listed on the patent are Johannes Winterot, Dietmar Schmidt, and Dieter Schau.

According to its abstract, the patent protects an arrangement for examining one or more specimens arranged in vessels or on carriers by transmitted light or incident light by imaging and/or detecting at least a portion of the specimen volume through the specimen vessel or specimen carrier by a CCD camera. This is followed by an evaluating unit, wherein, advantageously, an incident illumination is likewise effected through the specimen vessel or specimen carrier, used to excite specimen emission, preferably fluorescence excitation, the abstract states.


Columbia University has been awarded US Patent No. 6,823,826, “Method and system for analyzing multi-dimensional data.”

Inventors listed on the patent are Rafael Yuste, Vikram Kumar, and Robert Froemke.

According to its abstract, the patent protects a method for analyzing a sequence of data arrays. A selection of at least one type of region of interest and at least one region of interest from said data arrays is made. The sequence of data arrays are then transformed into a simplified data array. Events of interest in the selected regions of interest are then detected and stored in a second simplified data array. The data is then analyzed to determine relationships between the detected events of interest, the abstract states.


Molecular Devices has been awarded US Patent No. 6,825,921, “Multi-mode light detection system.”

Inventors listed on the patent are Douglas Modlin, John Owicki, Jon Peterson, Todd French, Carl Wright, Jeanne Ruiz, and Lorne Bechtel.

According to its abstract, the patent protects an apparatus and methods for combining multiple modes and methods of optical detection, postprocessing, and/or feedback loops in bioanalytical measurements. The methods may include positioning a composition at an examination site in a multi-mode instrument; detecting light transmitted from the composition using the multi-mode instrument in a first optical measurement mode; detecting light transmitted from the composition using the multi-mode instrument in a second optical measurement mode, the second mode being different than the first mode; and computing a quantity related to a property of the composition using the light detected in at least one of the optical measurement modes, the abstract states. These steps may be performed on one or more samples, simultaneously and/or sequentially, and the quantity may relate to photoluminescence, chemiluminescence, absorption, and/or scattering, among others, the abstract states.


The Dana-Farber Cancer Institute has been awarded US Patent No. 6,830,892, “Lentiviral vector system for high quantity screening.”

Inventors listed on the patent are Wayne Marasco and Sandra Ogueta.

According to its abstract, the patent protects a method of screening for a target molecule from a group of potential target molecules. The method involves using a library of lentiviral vectors where the members encode the group of target molecules, then transducing a group of cells and screening the transduced cell for a desired phenotype. The cell(s) displaying the desired phenotype is selected and the target molecule is identified, the abstract states.


OmniGene Bioproducts has been awarded US Patent No. 6,830,898, “Microorganisms and assays for the identification of antibiotics.”

Inventors listed on the patent are Rogers Yocum and Thomas Patterson.

According to its abstract, the patent protects methods for the identification of compounds and compositions useful as antibiotics and antibacterial agents. In particular, the invention features methods for the identification of modulators of a previously unidentified target protein, termed CoaX. The patent protects high-throughput assay systems as well as assay kits for the identification of CoaX modulators, the abstract states. Also described are coaX nucleic acid molecules and purified CoaX proteins, as well as recombinant vectors and microorganisms including the gene, coaX, the abstract states.