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Yu-Show Fu, Henrich Cheng, and Abbott Laboratories Awarded US Patents

Yu-Show Fu and Henrich Cheng have been awarded US Patent 7,252,995, “Method of generating neurons from stem cells and medium for culturing stem cells.”
The patent discusses a method of generating neurons from stem cells which involves culturing neurons in a medium and culturing the stem cells in the resultant mixture, the abstract states. The patent also discusses a medium for culturing stem cells prepared by culturing neurons in a base culture medium.

Abbott Laboratories has been awarded US Patent 7,252,992, “Cell line and uses thereof.”
The inventors listed on the patent are Dennis Fry, Christine Collins, and Brian Dayton.
According to the abstract, the patent relates to a novel cell line, referred to as T42402I3.4.2, and to uses of this cell line. For example, the cell line may be used in the production of recombinant melanin concentrating hormone receptor protein and in the identification of antagonists, inverse agonists, and receptor agonists.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.