Skip to main content
Premium Trial:

Request an Annual Quote

Will Molecular Devices Acquisition of Axon Affect Cellectricon?

Premium

Cellectricon’s single-cell capillary electroporation technology, ElectroFlow, is used to introduce foreign molecules into individual cells by applying an electrical discharge to the cell membrane. Lindberg told Inside Bioassays that the company is heavily promoting the technology for high-throughput screening using siRNA.

However, like traditional electroporation, the technology can also be used to introduce any impermeable molecules into the cell, such as DNA, RNA, chemical compounds, and molecular probes.

In fact, last October Cellectricon licensed the electroporation technology to Axon Instruments, a potential competitor for Cellectricon’s microfluidics platform for lead optimization screening of ion channels. Axon has in turn incorporated the technology into its Axoporator single-cell electroporation instrument, which the company is marketing primarily as a transfection tool for both screening applications and basic research.

Inside Bioassays asked Lindberg how he thought Molecular Devices’ pending acquisition of Axon would change the nature of this relationship and the cell-based screening market.

“I don’t know for sure — I think very few people do. But what is clear to me is that Molecular Devices has nothing below the 96-well format. Now they get the ImageXpress and PatchXpress. What will happen with the entire neurosciences business — from amplifiers to the lab bench version of a transfection instrument — I don’t know. But for me, it’s pretty clear that it doesn’t fully fit the Molecular Devices portfolio, including the amplifiers and everything for patch clamp.”

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.