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WiCell Research Institute

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WiCell Research Institute Debuts Stem Cell Bank
 
The WiCell Research Institute this week said that it is launching a stem cell bank to distribute cell lines beyond the 21 lines that are eligible for federal funding and distribution through the National Stem Cell Bank.
 
The WiCell International Stem Cell Bank is initially offering three induced pluripotent stem cell lines derived in the laboratory of James Thomson, a professor of anatomy at the University of Wisconsin-Madison and director of regenerative biology at the Morgridge Institute for Research, part of the new Wisconsin Institutes for Discovery.
 
WiCell said it hopes to add additional cell lines, such as disease model cell lines, from other providers locally and worldwide to the WISCB in the near future.
 
To obtain cells, researchers must complete an agreement ensuring the cells will be used only for non-profit research and pay a $900 per vial transfer/cost recovery fee plus shipping costs. In addition, the WiCell Research Institute will provide technical support for the long-term establishment of the iPS cells.

The Scan

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.

Study Explores Animated Digital Message Approach to Communicate Genetic Test Results to Family Members

In the Journal of Genetic Counseling, the approach showed promise in participants presented with a hypothetical scenario related to a familial hereditary breast and ovarian cancer syndrome diagnosis.

Computational Tool Predicts Mammalian Messenger RNA Degradation Rates

A tool called Saluki, trained with mouse and human messenger RNA data, appears to improve mRNA half-life predictions by taking RNA and genetic features into account, a Genome Biology paper reports.

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.