Scientists at the Whitehead Institute for Biomedical Research and the Massachusetts Institute of Technology have developed a new method for producing human induced pluripotent stem cells from which the lentiviral reprogramming factors have been excised.

A Whitehead researcher said this week that the cells, derived from patients with sporadic Parkinson's disease, remained pluripotent and revealed a gene-expression profile that more closely resembled human embryonic stem cells than human iPS cells still carrying the reprogramming factors.

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