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Washington University in St. Louis

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Washington University in St. Louis has been awarded US Patent 7,449,306, “Systems and methods for screening pharmaceutical chemicals.”
 
Inventors listed on the patent are Elliot Elson, William McConnaughey, and Tetsuro Wakatsuki.
 
As stated in the abstract, the patent provides a method for obtaining a response of a tissue model system to an activator, which includes contacting a bio-artificial tissue model system with an activator and measuring cellular mechanical response comprising contractile force and tissue stiffness. A method for obtaining a response of a tissue model system to an activator includes contacting a bio-artificial tissue model system with an activator and measuring cellular mechanical response comprising contractile force and hysteresis.

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