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Thermo Fisher Scientific, BioFocus DPI, DiscoveRx

Thermo Fisher Scientific this week launched its Reading Room web site, which is dedicated to all aspects of microplate reading.
The interactive tools and supporting material ensure that scientists can make informed choices about their use of Thermo Scientific microplate readers and accessories, the company said.
The Reading Room includes an “Application Zone,” which provides a comprehensive directory of downloadable application notes listed both by product and technology. Furthermore, the “Reference Section” provides details of scientific peer-reviewed publications where Thermo Scientific microplate readers have been used. Researchers can also submit their own stories about their use of Thermo Scientific microplate readers through the “Readers in Action” tool. 
The web site can be found at

BioFocus DPI this week announced the release of five hit-finding compound libraries targeting the ion-channel gene family. These libraries are specifically aimed at voltage-dependent channels and ligand-gated channels, two of the most commonly chosen classes of ion channels for drug discovery. 
The three new SoftFocus ion channel libraries target voltage-dependent channels, primarily focusing on sodium and calcium channels to complement BioFocus DPI’s earlier libraries focused on potassium channels. These libraries were designed using BioFocus DPI’s proprietary chemogenomic tool Helical Domain Recognition Analysis.
The two new FieldFocus libraries target members of the transient receptor potential channel, including TPRV, TRPM and TRPAs, and were created in collaboration with Cresset BioMolecular’s FieldPrint technology.

DiscoveRx this week announced the launch of its GPCR profiling services utilizing its PathHunter beta-arrestin technology platform. The profiling panel includes a list of GPCRs representing 32 ligand families.
All GPCR-expressing cell lines are based on the PathHunter Arrestin technology, which measures GPCR activation without the need of target over-expression, force coupling, imaging, or second messenger detection.

The Scan

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.

Study Presents New Insights Into How Cancer Cells Overcome Telomere Shortening

Researchers report in Nucleic Acids Research that ATRX-deficient cancer cells have increased activity of the alternative lengthening of telomeres pathway.

Researchers Link Telomere Length With Alzheimer's Disease

Within UK Biobank participants, longer leukocyte telomere length is associated with a reduced risk of dementia, according to a new study in PLOS One.

Nucleotide Base Detected on Near-Earth Asteroid

Among other intriguing compounds, researchers find the nucleotide uracil, a component of RNA sequences, in samples collected from the near-Earth asteroid Ryugu, as they report in Nature Communications.