Surface Logix has been awarded US Patent 7,285,412, “Device for magnetic immobilization of cells.”
Inventors listed on the patent are Rocco Casagrande, Evelyn Wang, Gregory Kirk, Michael Nussbaum, Enoch Kim, and Aaron Raphel.
According to the abstract, the invention discusses an apparatus and methods that immobilize one or more cells associated with magnetic material on a substrate on which are located one or more magnetic receptacles. The device also arrays cells associated with magnetic material on a substrate that has a pattern of magnetic receptacles. The size of the magnetic receptacle determines the number of target cells that the apparatus is capable of immobilizing. The size of the magnetic receptacle is defined by the strength of a localized magnetic field gradient. The localized magnetic field gradient may be derived from permanent magnets embedded in the substrate or an external magnet whose strength is focused by objects of highly permeable magnetic material. The apparatus comprises a removable cell delivery device and a substrate, which contains one or more magnetic receptacles.
Caliper Life Sciences has been awarded US Patent 7,285,411, “High throughput screening assay systems in microscale fluidic devices.”
Inventors listed on the patent are John Parce, Anne Kopf-Sill, and Luc Bousse.
The patent provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays, according to its abstract. In particular, the devices and methods described in the patent are useful in screening large numbers of different compounds for their effects on a variety of chemical, and preferably, biochemical systems.