Researchers at Stanford University and the University of California at San Francisco have developed a phosphospecific flow cytometry technique to profile signaling at the single-cell level, including molecules downstream of the granulocyte-macrophage colony-stimulating factor receptor and molecules closely associated with Ras signaling.
The cell populations will be evaluated for the presence of primary juvenile myelomonocytic leukemia, or JMML, cells with altered signaling behavior correlated with disease physiology.

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