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Sigma-Aldrich, Cellomics, TAP, ATCC

Sigma-Aldrich Signs on New Batch of Academics for RNAi Partnership Program
Sigma-Aldrich said this week that researchers from six academic institutions have joined its RNAi Partnership Program.
The researchers are from the Wistar Institute, Mayo Clinic, Tufts University, Princeton University, Moores Cancer Center at the University of California, San Diego, and Washington University in St. Louis.
Sigma formed its RNAi Partnership Program in April to provide researchers with RNAi tools, including products, new technologies, and reagents, as well as access to Sigma-Aldrich’s functional genomic portfolio.
The portfolio includes access to the lentivirus-based Mission TRC shRNA libraries that target more than 15,000 human and mouse genes.

Cellomics Expands HCS Training to Include ‘Advanced’ Topics
Fisher Biosciences unit Cellomics this week said that it has expanded its continuing education curriculum with the introduction of advanced courses in high-content screening applications.
The new courses will offer customers training for specific uses of HCS in biology research and therapeutics, including fields such as oncology, neurobiology, and toxicology.
Cellomics said that two classes are scheduled for this fall. HCS 202 will be offered Oct. 25 and 26, and will cover HCS for cancer research in cell-cycle regulation, apoptosis, necrosis, and angiogenesis. The second course, HCS 201, will be held Dec. 5 and 6, and will focus on HCS techniques for toxicology, such as the application of cytotoxicity and genotoxicity assays.
Additional classes to be scheduled in the spring will train customers in applications for neurobiology and cell signaling, among other topics.
All courses are held at Cellomics’ training facility in Pittsburgh. Registration and general information on the course are available on Cellomics web site,

TAP Installs Pair of Automated Cell Culture Systems at ATCC Facility
The Automation Partnership this week said that it has installed two of its SelecT automated systems for cell culture at the American Type Culture Collection.
The SelecT system allows for unattended culturing of multiple cell lines and assay-ready plate generation. It is currently used by more than 30 pharma and biotech companies internationally, TAP said.
The SelecT system will be used by ATCC to increase cell culturing productivity of more than 1,000 different mammalian cell lines, TAP said.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.