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Serologicals, LINCO, NIST

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Serologicals to Acquire LINCO for $75M to Expand Multiplexing Products Portfolio

Serologicals announced this week that it has made an agreement to acquire LINCO, a life sciences company that focuses on supplying research assays and test kits for the Luminex-based multiplexing platform and other immunoassays.

Under terms of the agreement, Serologicals will pay $64.5 million in cash for the LINCO business, which has 109 employees, plus an additional $10.3 million for the land and buildings currently occupied by LINCO in St. Louis, Mo.

Serologicals said it expects the acquisition to be completed next month.


NIST Extends Call for RNA Sequences

The National Institute of Standards and Technology has extended to April 28 the deadline for RNA sequence contributions to be included in its first round of testing.

The sequences, which will be used in a manner mimicking portions of typical mammalian mRNA transcripts, must be released to the public domain.

NIST is building a library of RNA reference materials as part of a program with the External RNA Controls Consortium. The library of controls is expected to lead to commercial products.

Further details on selection of sequences can be found at http://www.clsi.org.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.