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SC Biosciences and Cyntellect, Bristol-Myers Squibb and Labcyte, and Accelrys and Sigma-Aldrich

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SC Biosciences to Market Cyntellect Cell Line Development Platform in Japan

Cyntellect, of San Diego, said last week that it has signed an agreement with Japan’s SC Biosciences in which SC Biosciences will serve as the limited exclusive Japanese marketing partner for Cyntellect’s Cell Xpress cell line development service. Financial terms of the deal were not disclosed.

Cell Xpress is based on Cyntellect’s LEAP (Laser-Enabled Analysis and Processing) platform, which enables high-throughput in situ measurement of cell protein secretion on an individual cell basis, coupled with laser-based elimination of undesired cells, to directly clone cells with the highest expression levels, Cyntellect said.

Cyntellect will directly market Cell Xpress in the US and Europe, and will consider additional marketing partners for other Asian territories, Fred Koller, Cyntellect’s president and chief technology officer, said in a statement.


Bristol-Myers Squibb Buys Two Acoustic Compound Reformatters from Labcyte

Labcyte announced last week that Bristol-Myers Squibb has purchased two of its Labcyte Echo 550 compound reformatters following the completion of a beta-testing program. Financial terms of the deal were not disclosed.

The Echo 550 transfers liquids and cells using sound. The direct acoustic transfer, according to the company, has variation values of less than 5 percent, and is designed for the replication and reformatting of compound libraries, as well as plate compression or expansion from 384- and 1,536-well microplates.


Accelrys Integrates Sigma-Aldrich Chemical Compound Catalogs into Cheminformatics Database

Informatics firm Accelrys announced last week that it will incorporate Sigma-Aldrich’s chemical compounds catalog into Accelrys’ chemical suppliers database, CAP (Chemicals Available for Purchase).

The CAP database is accessible from desktop PCs, and allows researchers to retrieve commercially available chemicals through chemical search technologies, Accelrys said.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.