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Sangamo Biosciences and Carnegie Mellon Win US Patents Related to Cell-Based Assays

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Sangamo Biosciences has been awarded US Patent No. 6,989,269, "Cells for drug discovery."

Casey Case is the lone inventor listed on the patent.

According to its abstract, the patent protects compositions and a method useful for screening a compound for its interaction and/or effect with a molecular target and/or cellular processes.


Carnegie Mellon University has been awarded US Patent No. 6,989,275, "Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods."

Alan Waggoner is the lone inventor listed on the patent.

According to its abstract, the patent protects luminescent dyes and methods for covalently attaching the dyes to a component or mixture of components so that they may be detected and/or quantified by luminescence detection methods. The dyes are cyanine and cyanine-type dyes that contain or are derivatized to contain a reactive group. The reactive group is covalently reactive with amine, hydroxyl, and/or sulfhydryl groups on the component so that the dye can be covalently bound to the component. In addition, the dyes are preferably soluble in aqueous or other media in which the component is contained. The components to be labeled can be either biological materials, such as antibodies, antigens, peptides, nucleotides, hormones, or drugs; or non-biological materials, such as polymers, glass, or other surfaces. Any luminescent or light-absorbing detecting step can be employed in the method of the invention, the abstract states.

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