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Roger Tsien, Osamu Shimomura, Martin Chalfie

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The Royal Swedish Academy of Sciences said this week that the 2008 Nobel Prize in Chemistry was awarded to Roger Tsien, a Howard Hughes Medical Institute investigator at the University of California, San Diego; Osamu Shimomura of the Marine Biological Laboratory; and Martin Chalfie of Columbia University. The three were honored for their discovery and development of the green fluorescent protein.
 
According to the Royal Swedish Academy, this year's Nobel Prize in Chemistry rewards the initial discovery of GFP and a series of important developments that have led to its use as a molecular tag in biomedical research. 

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.