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New Products: Dec 5, 2008

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Roche Applied Science said this week that it introduced the new xCELLigence RTCA MP instrument two weeks ago. In comparison with the xCELLigence RTCA SP, the new RTCA MP Instrument has a higher throughput capacity and it is more versatile, which enables application on a wider range of experimental set-ups, the company said.
 
The new system features six E-Plate 96 microtiter plates, as opposed to only one in the RTCA SP. Each E-Plate can be individually addressed in independent experiments, to allow a group of researchers to work simultaneously. According to Roche, the first systems have already been delivered to major pharmaceutical companies.
 
The xCELLigence technology features a micro-electronic biosensor built into each well of the standard 96-well E-Plate. A cell which has contact with the sensor changes the electrical impedance between the microelectrodes.
 
Each change in the cell's status — for example, changes in cell adhesion, cytotoxicity, cell proliferation, cell-cell interactions, and morphological changes — leads to changes in the impedance measurements, and can therefore be detected in real time. Labeling of the cells or the use of reporters is not necessary.

The Scan

Could Mix It Up

The US Food and Drug Administration is considering a plan that would allow for the mixing-and-matching of SARS-CoV-2 vaccines and boosters, the New York Times says.

Closest to the Dog

New Scientist reports that extinct Japanese wolf appears to be the closest known wild relative of dogs.

Offer to Come Back

The Knoxville News Sentinel reports that the University of Tennessee is offering Anming Hu, a professor who was acquitted of charges that he hid ties to China, his position back.

PNAS Papers on Myeloid Differentiation MicroRNAs, Urinary Exosomes, Maize Domestication

In PNAS this week: role of microRNAs in myeloid differentiation, exosomes in urine, and more.