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Regents of the University of Michigan, Korea Research Institute of Bioscience and Biotechnology Awarded US Patents

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The Regents of the University of Michigan have been awarded US Patent 7,387,896, “MicroRNA vectors.”
 
The inventors listed on the patent are David Turner, Kwan-Ho Chung, and Paresh Patel.
 
The patent relates to gene silencing, according to its abstract, and in particular to compositions of microRNA sequences and vectors. The patent also describes methods of synthesizing these microRNA sequences in vitro and in vivo, and methods of using them to regulate gene expression.
 

 
The Korea Research Institute of Bioscience and Biotechnology has been awarded US Patent 7,387,895, “Monoclonal antibody specific for PPAR gamma, hydridoma cell line producing the same, and method for detecting regulator related to diseases, including inflammation, cancer and metabolic diseases, using the same.”
 
The inventors listed on the patent are Doyoung Yoon, Haesook Lee, Minchul Cho, Kyungae Lee, Kyungjoo Cho, Jeongwoo Kang, Junghyun Shim, Jongseok Lim, Jintae Hong, Heegu Lee, and Yongkyung Choe.
 
As stated in its abstract, the patent discusses a hybridoma cell line producing a PPAR gamma-specific monoclonal antibody, and a method for detecting a PPAR gamma ligand related to the progression of difficult diseases, such as cancer, inflammation, and metabolic diseases such as obesity and diabetes, using the PPAR gamma-specific monoclonal antibody. This PPAR gamma-specific monoclonal antibody and the method for screening a PPAR gamma ligand using the monoclonal antibody will be commercially used for screening a PPAR gamma regulator related to diseases such as inflammatory, cancer, and metabolic diseases. It also will serve as a useful tool for analyzing the function of such a ligand.