Researchers at Columbia University and Prolexys Pharmaceuticals have used a pull-down assay to identify a target for the experimental small molecule anti-tumor agent erastin.
 
Prolexys is also using erastin as an experimental probe to identify the protein target and better understand its mechanism of action, with the goal of creating a drug-discovery franchise around the biology of the protein target, Sudhir Sahasrabudhe, Prolexys’ CSO and co-founder, told CBA News this week.
 

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The US National Institutes of Health has developed guidelines to gauge whether frail chimpanzees are healthy enough to be moved to a retirement sanctuary.

Osamu Shimomura, who won the 2008 Nobel Prize in Chemistry for his work on green fluorescent protein, has died.

In PLOS this week: analytical approach for finding new genetic associations, analysis of Streptococcus pyogenes-infecting viruses, and more.

Stat News reports that the head of IBM Watson Health is leaving her post.