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Platypus Technologies

Platypus Technologies this week announced the addition of the Oris Universal cell migration assembly kit, 96-well format, to its product line of cell-based assays. Oris cell seeding stoppers replace membrane-based, cell culture inserts to generate real-time results in chemokinesis or 2D closure studies.
Unlike the original Oris cell migration kits, the Oris Universal assembly kit allows scientists to coat the 96-well plate with any extracellular matrix component to create a migration or invasion assay. A 2D closure assay can be designed by leaving the plate uncoated.
The Oris cell seeding stoppers are then inserted into each well, where the stopper tip creates a protected 2-mm round zone in the center of each well. Cells are seeded, allowed to adhere, and then the stoppers are removed, exposing a detection zone into which cells can move.
An overlay of an ECM on the cells after stopper removal provides a 3D environment for studying invasion. Cell movement can be monitored in real time by staining and viewing cells with a microscope or digital imaging system. A detection mask is snapped to the bottom of the plate, permitting quantitation of stained cells using a plate reader.

The assay is offered as a 1-plate starter pack and as a 5-plate multi-pack. A collagen I coated plate version of the Oris assembly kit is also available.

The Scan

More Boosters for US

Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes.

From a Pig

A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports.

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.