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New Products: Dec 19, 2008

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PerkinElmer this week announced the release of 11 new AlphaScreen SureFire assay kits for the rapid detection of full-length kinase activation in cell lysates. The new kits were launched at the 48th annual meeting of the American Society for Cell Biology, held this week in San Francisco, Calif. 
 
The addition of the 11 new assay kits brings the total number of AlphaScreen SureFire kits to 39. Among the new kits are two that measure direct phosphorylation of cellular receptors: Insulin and IGF-1 receptors.
 
The latest assay kits include: Phospho-ALK (Tyr1586); Phospho-ALK (Tyr1604); Phospho-Chk-1 (Ser345);Phospho-c-Jun (Ser63); Phospho-c-Jun (Ser73); Phospho-EGF receptor (Tyr1068); Phospho-Elk-1 (Ser383); Phospho-ErbB2 (Tyr1221/1222); Phospho-IGF-1 Receptor (Tyr1135/1136); Phospho-Insulin receptor (Tyr1150/1151); and Phospho-mTOR (Ser2448).
 

 
PerkinElmer also announced this week at the ASCB annual meeting that it has expanded its AlphaLISA "No Wash" assay line.
 
The AlphaLISA portfolio now comprises 27 kits — including kits for detecting biomarkers associated with inflammation, cancer, neurodegeneration, metabolic disorders, and angiogenesis.           
 

 
Nikon Instruments this week at the ASCB annual meeting in San Francisco launched its Virtual Adjustable Aperture System, or VAAS, a confocal imaging method for post-acquisition recovery of data normally lost during the course of the experiment. This data recovery is accomplished by collecting emission photons that normally are rejected by the emission side pinhole, traditionally used at the 1 airy disk size.
 
VAAS technology allows for virtual adjusting of the confocality and sensitivity of data post-acquisition, as well as collecting more photons during the initial image acquisition to enable image reconstruction with a greatly improved signal-to-noise ratio, the company said.
 
VAAS uses two pinholes to collect emitted photons: a standard-sized pinhole to enable confocality, and a pinhole with a diameter three times larger to capture more of the emitted fluorescence without increasing the out-of-focus background detection. The manufacturer said that VAAS can reduce the out-of-focus haze signal without reducing the signal from the focal plane.
 
VAAS Detection is offered as an upgrade option to Nikon's A1 series of confocal laser point scanning systems.
 

 

Innovatis launched its new Cedex XS cell analyzer in the US this week at the ASCB annual meeting in San Francisco.  The Cedex XS is a semi-automated, image-based cell analyzer capable of delivering cell concentration, viability using the Trypan blue exclusion method, cell morphology, cell aggregation, and growth data from sample volumes as small as 10 µl.

The Scan

Not Yet a Permanent One

NPR says the lack of a permanent Food and Drug Administration commissioner has "flummoxed" public health officials.

Unfair Targeting

Technology Review writes that a new report says the US has been unfairly targeting Chinese and Chinese-American individuals in economic espionage cases.

Limited Rapid Testing

The New York Times wonders why rapid tests for COVID-19 are not widely available in the US.

Genome Research Papers on IPAFinder, Structural Variant Expression Effects, Single-Cell RNA-Seq Markers

In Genome Research this week: IPAFinder method to detect intronic polyadenylation, influence of structural variants on gene expression, and more.