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PerkinElmer, Labcyte, and Nikon

PerkinElmer this week launched the PhotoKinesis accessory for its UltraVIEW live-cell imaging system.
The PhotoKinesis accessory was designed to enable fluorescence recovery after photobleaching and similar techniques on the UltraVIEW. The accessory also includes “Track-It” on-demand photoactivation and photoswitching, which provides users with greater control over their experiments, PerkinElmer said.

Labcyte this week announced the release of two software products for setting up dose-response assays and for facilitating cherry picking. Both products support the company’s Echo 550 and Echo 555 acoustic energy-based liquid handlers.
The Dose-Response software makes it easier for users of the Echo systems to set up multi-point does-response assays typical of the types of analyses used for IC50 and EC50 determinations, Labcyte said.
The Cherry-Picking software makes it easier for Echo users to choose specific compounds from library source plates and transfer them to assay plates in a variety of ways, including interplate and intraplate replicates, variable volume transfers, and pooled transfers.

Nikon this week launched the BioStation IM, a ‘hands-off’ system for managing, observing, and recording the growth of cells in culture.

The system combines the environmental control capabilities of a CO2 incubator with and optical monitoring system that enables drift-free, live-cell imaging. Cultures can be imaged at 10X to 80x magnifications under phase contrast, as well as using epifluorescence illumination. The system also comes in two versions: one with a long working distance lens to work with plastic Petri dishes and another with a high numerical aperture lens optimized for thin-bottom glass Petri dishes, Nikon said.

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.