Skip to main content
Premium Trial:

Request an Annual Quote

Patent Watch: Mar 6, 2009


NPS Pharmaceuticals has been awarded US Patent 7,498,141, "Assay system for GLP-2 receptor ligands."

The inventors listed on the patent are Lidia Demchyshyn and Hong Wang.

The patent claims a method for measuring the contractility of intestinal tissue upon treatment with GLP-2 or a GLP-2 ligand, according to its abstract. Also described is an assay which directly measures the activity of GLP-2 or GLP-2 ligands ex vivo, and permits the screening of putative GLP-2 ligands in native tissue.

Shigeki Higashiyama and Daisuke Nanba have been awarded US Patent 7,498,127, "Method of screening cell growth inhibitor and cell growth inhibitor."

Its abstract states that the patent provides a method for screening a cytostatic agent, characterized by determining the effect of inhibiting intracellular signaling mediated by a remaining fragment of a cell membrane-anchored growth factor and the cytostatic agent.

Meso Scale Technologies has been awarded US Patent 7,497,997, "Assay cartridges and methods of using the same."

The inventors listed on the patent are Eli Glezer, Jonathan Leland, Mark Billadeau, Joseph Leginus, Bandele Jeffrey-Coker, Jeff Debad, Koustubh Phalnikar, and Sriram Jambunathan.

As stated in the abstract, the patent describes assay modules, preferably assay cartridges, and reader apparatuses that may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode-induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components that may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, and dry reagent pill zones.

The Scan

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.

Study Presents New Insights Into How Cancer Cells Overcome Telomere Shortening

Researchers report in Nucleic Acids Research that ATRX-deficient cancer cells have increased activity of the alternative lengthening of telomeres pathway.

Researchers Link Telomere Length With Alzheimer's Disease

Within UK Biobank participants, longer leukocyte telomere length is associated with a reduced risk of dementia, according to a new study in PLOS One.

Nucleotide Base Detected on Near-Earth Asteroid

Among other intriguing compounds, researchers find the nucleotide uracil, a component of RNA sequences, in samples collected from the near-Earth asteroid Ryugu, as they report in Nature Communications.