Novartis Vaccines and Diagnostics has been awarded US Patent 7,422,861, “Oligonucleotide transfection screening method.”
The inventors listed on the patent are Ronald Zuckermann, Christoph Reinhard, Anne Jefferson, and Eric Beausoleil.
As stated in its abstract, the patent provides different-sequence peptoids, including lipid- and sterol-conjugated peptoids, that have been found to be effective in the transfection of cells with oligonucleotides. Combinatorial libraries of such peptoids can be screened efficiently in a high-throughput format, and selected peptoids can then be identified post-screening.
The Food Industry Research and Development Institute of Taiwan has been awarded US Patent 7,422,736, “Somatic pluripotent cells.”
The inventor listed on the patent is Shiaw-Min Hwang.
The patent abstract describes a cultured somatic animal cell having a normal karyotype. The cell develops into an embryoid body when induced in vitro, or develops into a teratoma when introduced into a severe combined immunodeficient mouse. A method of producing such a cell is also discussed.