Skip to main content
Premium Trial:

Request an Annual Quote

Nikon Instruments, Sigma-Aldrich

Nikon Instruments this week introduced the Eclipse MA200, an inverted materials microscope with a design that has been optimized for digital imaging and ergonomic efficiency, the company said.
The MA200 uses automatically combines captured images with data and offers a new box design that facilitates access to the sample on the stage and nosepiece, while making the footprint size one third of the conventional model, according to the company.
The MA200 delivers bright, high resolution, and high contrast images. The newly developed 1X objective lens enables macro observation with an actual field view of 25mm. In addition, the MA200 offers a wide range of contrast methods including episcopic bright field, episcopic dark field, DIC, simple polarizing, and episcopic fluorescence.
The intelligent manual nosepiece will output the objective position and internal magnification data to DS-L2 and NIS-Elements for automatic scale calibration. The scales size will automatically be calibrated when the objective magnification is changed. Large image stitching is also possible through the optional stitching function in the NIS-Elements software. Additionally, by combining the Metalo software module, the system will be optimal for JIS and ASTM standard compliant metallurgical analysis.
The Eclipse MA200 is the succeeding model of the TME300/200 and the advanced model of the Eclipse MA100.

Sigma-Aldrich this week launched its CompoZr platform of zinc finger nuclease reagents.
Initially offered as a customized service for developing ZFNs for specific gene targets, the CompoZr ZFN platform will eventually include ZFN-based kits for targeted transgene insertion, and a catalog of off-the-shelf reagents for commonly studied gene targets, gene families, and pathways. 
All CompoZr reagents are functionally validated in a cell line appropriate for the intended organism of interest, and customers are provided with full protocols for use of their reagents and troubleshooting support from Sigma Life Science’s technical team, the company said. 

The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.