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New Products: Jan 23, 2009


Applied BioPhysics announced this week that it is launching its electric cell-substrate impedance sensing models Z and Zθ, which provide multiple frequency measurements and comprehensive data analysis capabilities, as well as broader bandwidth, increased speed, and higher sensitivity than previous models.

ECIS can measure cell behaviors including cell attachment and spreading on extracellular matrix proteins, cell migration, extravasion of endothelial cell layers, barrier function, signal transduction, cytopathic effects of viral infections, cytotoxicity, cell proliferation, and more.

In addition to measuring simple impedance, the ECIS Zθ system allows the user to measure complex impedance and report its constituent components of resistance and capacitance over a spectrum of frequencies.

The new ECIS Z and ECIS Zθ now have the ability to interface with both 16- and 96-well stations.

Both systems comprise a system controller, 16- and/or 96-well station options, laptop or desktop computer (PC or Mac), and integrated software based on Matlab and featuring a graphical interface. Both systems can be equipped with a flow system for specialized endothelial cell applications, as well as with the elevated field module to carry out automated wound-healing/migration and electroporation experiments.

The Automation Partnership this week announced the North American launch of CellCelector, which the company claims is the world’s first commercial automated stem cell picker.

CellCelector comprises an inverted Olympus microscope, robotic arm, and liquid handling station, all fully integrated with image acquisition and analysis software. This walkaway system allows researchers to set parameters for cell or colony types they want, including size, proximity to other colonies, or roundness, and the picking tool on the robotic arm dispenses cells into a microplate well in 30 seconds.

The CellCelector can fit into any standard laminar flow hood, to ensure that cells remain contamination free. The system can also be fitted with an autoclave-compatible metal tool for scraping adherent cells, or a disposable glass capillary for picking single cells.

CellCelector, developed by German cell biology automation shop Aviso, is currently being used in universities and institutes across Europe with murine and human stem cells.

Cell Biosciences this week announced the launch of its first kits for the analysis of specific oncoproteins on the Firefly 3000 protein analysis system. The new kits are optimized for characterization of proteins in the MEK and ERK families, the company said.

The Firefly 3000 system is a nanofluidic immunoassay system designed to analyze extremely small biological samples. By using the new analysis kits on the Firefly 3000 system, researchers can obtain detailed profiles of MEK and ERK signaling in as few as 25 cells, according to the manufacturer.

Hudson Control Group this week introduced the VaryScreen I, a multi-assay screening and development system.

The company said that VaryScreen allows investigators to rapidly switch assays, including six of the most commonly performed assays today: AlphaScreen, luminescence, fluorescence resonance energy transfer, enzyme-linked immunosorbent assay, fluorescence polarization, and ultraviolet/visible absorbance.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.