Molecular Devices last week announced the introduction of Transil Membrane Affinity and Transil Human Serum Albumin Binding assay kits, reagent products for ADME assay screening.
The Transil Membrane Affinity kit provides data that correlates better to in vivo studies compared with the more conventional water/octanol partitioning assays because it uses beads that are coated with a lipid bilayer that mimic interactions between compounds and cell membranes, MDCC said. The HSA Binding Assay has beads that have been coated with HAS and pre-dispensed into a microplate format. Both kits area available in 96- or 384-well formats, MDCC said.
Amresco said this week that it has launched Trypan Blue Solution, 0.4 percent, as a ready-to-use solution for determining cell viability. With the assay, dead cells appear blue while viable cells exclude the dye, Amaresco said.
Sigma-RBI, a division of Sigma-Aldrich, said last week that it has released the Sigma-RBI Ion Channels Brochure. This brochure provides an overview of the two main categories of ion channels: voltage-gated and ligand-gated, Sigma said. The structure, function, and role in disease of more than a dozen types of ion channels are covered in charts, text, and graphics, Sigma said.
For more information and to receive a free copy of the brochure, go to http://sigma-aldrich.com/ionchanbrochure.