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Molecular Devices IMAP Substrate Finders for Tyrosine Kinases and Serine/Threonine Kinases, GE Healthcare s SPA for GPCR Membranes, and SRI Institute s Ion Channels in Drug Discovery and Development Conference


Molecular Devices last week introduced its IMAP Substrate Finder for tyrosine kinases. Together with the company’s Substrate Finder for serine/threonine kinases, the products provide substrates for the two categories of kinases that make up the human kinome, Molecular Devices said.

GE Healthcare said last week that it has launched SPA (scintillation proximity assays) for GPCR membranes. The assays comprise SPA beads and radioligands from GE Healthcare with GPCR receptor membranes from Euroscreen.

According to the company, the new assays allow researchers working in high-throughput screening to use pre-developed assay protocols for GPCR receptor-ligand binding studies. The protocols offer time savings of as many as 15 days, the company claimed.

SRI Institute said that its Fourth Annual Ion Channels in Drug Discovery and Development conference will be held Oct. 4 and 5 in Philadelphia. The conference will feature keynote speakers Irwin Levitan, professor at the University of Pennsylvania, and Alan Finkel, chief technology officer and senior vice president of Molecular Devices.


The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.