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Millipore, Promega, KD Scientific

Millipore this week announced the availability of its MEL cell lines, which are licensed, low-passage, human embryonic stem cells. The MEL-1 and MEL-2 hESC cell lines have been tested with Millipore’s HEScGRO media for human embryonic stem cell culture.
The MEL cell lines, developed by Melbourne, Australia-based Stem Cell Sciences in collaboration with Melbourne IVF and the Australian Stem Cell Center, are under license from the Australian National Health and Medical Research Council.

Promega this week announced the release of high-performance GloResponse luciferase reporter cell lines. The company said that its GloResponse NFAT-RE-luc2P HEK293 cell line and CRE-luc2P HEK293 cell line provide optimized luciferase reporter response to facilitate turnkey implementation. These cell lines can provide response dynamics of over 100 induction in as few as four hours with the CRE cell line, according to the manufacturer.

KD Scientific this week announced the launch ofits UltraSpense 2000 live-cell dispensing system. According to the company, the UltraSpense 2000 eliminates edge effects and delivers more viable cells more uniformly to 384-well microplates when compared to conventional peristaltic dispensers.

UltraSpense 2000 has a specially designed coated manifold that uniformly distributes material to all eight tips, the manufacturer said. This is combined with a proprietary pumping algorithm that overcomes the natural tendency for fluids to accumulate on the outside of the manifold tips.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.