A team of researchers at Merck has developed a genome-wide RNAi screening technique that may increase the dynamic range and decrease the variability in cell-based assays used for RNAi screening, which could facilitate reliable hit selection, according to their findings.
 
The investigators showed that the method, called T’fection, yielded a mean absolute deviation-based hit selection that identified physiologically relevant false negatives that standard-deviation-based methods missed.
 

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A new estimate places the last universal common ancestor to life on Earth as living 3.9 billion years ago, Inverse reports.

23andMe's Anne Wojcicki ponders DNA and what it means to be human in a New York Times essay.

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