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Leonard Herzenberg, Leonore Herzenberg, Krishna Kodukula, Stephen Chang, Gerald Newmin, Cisbio International

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Migrations

Invitrogen said this week that it has formed a flow cytometry scientific advisory board to be chaired by Leonard Herzenberg. Invitrogen also said that Leonore Herzenberg, Leonard's wife, will join the board as a member.

The Herzenbergs are both professors at Stanford University, and run the shared flow cytometry facility there. Len Herzenberg invented the fluorescence-activated cell sorter, and along with Lee has developed several methods and instrumentation related to flow cytometry. Invitrogen said the advisory board will help guide the company's efforts in product development for immunology, flow cytometry, and cell biology.


SRI International this week said that Krishna Kodukula has joined its biosciences division as senior director of system biology. Kodukula will help establish new programs and expand business opportunities, working with SRI's Center of Excellence in Infectious Disease and Biodefense, and Center of Excellence in Computational Biology, SRI said.

Kodukula joins SRI from Sarnoff, an SRI subsidiary. Prior to his time at Sarnoff, Kodukula co-founded Small Molecule Therapeutics and Pyxis Technology Solutions. He has also been an investigator with Bristol-Myers Squibb Pharmaceutical Research Institute and a fellow at the Roche Institute of Molecular Biology. He holds a PhD in biochemistry and botany from Utkal University in India.


MultiCell Technologies said this week that it has appointed Stephen Chang as CEO. He will also continue in his current role as president of MultiCell Technologies. Outgoing CEO Gerald Newmin will continue in his role as co-chairman and secretary of the company, MultiCell said. Chang joined MultiCell as president in 2005.

 

Products

Cisbio International this week announced the release of its second IP-One assay, called IP-One ELISA, at the GPCR Congress in Barcelona, Spain. The new assay complements Cisbio's existing IP-One HTRF assay to create a portfolio of assays for inositol(1)phosphate quantification and GPCR screening, the company said.

IP-One ELISA is a monoclonal antibody-based assay that detects IP1, a major product of the phosphatidyl inositol cascade, which correlates with Gq-coupled activity, Cisbio said.

The Scan

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.

Breast Cancer Risk Gene Candidates Found by Multi-Ancestry Low-Frequency Variant Analysis

Researchers narrowed in on new and known risk gene candidates with variant profiles for almost 83,500 individuals with breast cancer and 59,199 unaffected controls in Genome Medicine.

Health-Related Quality of Life Gets Boost After Microbiome-Based Treatment for Recurrent C. Diff

A secondary analysis of Phase 3 clinical trial data in JAMA Network Open suggests an investigational oral microbiome-based drug may lead to enhanced quality of life measures.

Study Follows Consequences of Early Confirmatory Trials for Accelerated Approval Indications

Time to traditional approval or withdrawal was shorter when confirmatory trials started prior to accelerated approval, though overall regulatory outcomes remained similar, a JAMA study finds.