Kathryn Horwitz and Jennifer Richer of the University of Colorado Health Sciences Center have been awarded US Patent No. 6,750,015, “Progesterone receptor-regulated gene expression and methods related thereto.”

According to its abstract, the patent discloses expression profiles of genes that are regulated by progesterone receptors, and particularly by progesterone receptor isoforms PR-A and PR-B. Methods for using such genes to identify progesterone receptor agonist and antagonist ligands are described.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.