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Immunex and LJL Biosystems are Among Recent Patent Winners

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Lam Nguyen, Miguel Bravo-Zanoquera, Albert Kellner, and Jeffrey Price have been awarded US Patent No. 6,839,469, “Multiparallel three-dimensional optical microscopy system.”

According to its abstract, the patent protects a method of volume imaging that is supported in an optical apparatus that simultaneously acquires multiple images from multiple focal planes in an image object. A plurality of image detectors is arranged with respect to an objective lens, while a plurality of reflective devices are disposed between the objective lens and the plurality of detectors to divide the light travelling through the objective lense to the detectors into channels, such that each channel is registered with a respective detector, the abstract states.


Immunex has been awarded US Patent No. 6,838,290, “Methods for screening compounds that affect IL-1 epsilon activity.”

Inventors listed on the patent are John Sims and Dirk Smith.

According to its abstract, the patent protects purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, the use of such polypeptides in cellular and immune reactions, the use of such polypeptides in screening for agonists or antagonists of IL-1 epsilon activity, and kits comprising such polypeptides.


LJL Biosystems has been awarded US Patent No. 6,838,051, “Integrated sample-processing system.”

Inventors listed on the patent are Samuel Marquiss, Christopher Cesar, Jon Petersen, David Stumbo, Amer El-Hage, Glenn Edwards, Douglas Modlin, Ley Leytes, and Samuel Burd.

The invention provides an integrated sample-processing system and components thereof for preparing and/or analyzing samples. The components may include a transport module, a fluidics module, and an analysis module, among others.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.