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GenoSpectra, Genetix, Open Biosystems, MultiCell Technologies


GenoSpectra last week announced the launch of QuantiGene Plex, the first available multiplexed gene expression profiling assay based on Luminex's xMAP technology.

According to GenoSpectra, QuantiGene Plex allows accurate and precise quantification of multiple mRNA targets in a single well without the need for RNA purification, reverse transcription, or target amplification. It also can detect percent differences in expression, rather than fold differences measured by current technologies, GenoSpectra said.

Genetix last week announced the launch of CloneSelect, the company's mammalian cell-line management system, at the European Society for Animal Cell Technology in Harrogate, UK.

According to Genetix, CloneSelect is a microplate-based system that integrates confluence determination, expansion, stratification, and cherry picking with automated plate tracking and data management. The system incorporates a bar code reader for the tracking of source, replicate, and subsequent daughter plates. All data from CloneSelect is compatible with common LIMS systems, Genetix said.

Open Biosystems announced last week the completion of its ExpressionArrest whole genome human short hairpin library.

According to Open Biosystems, the shRNA library was developed by Cold Spring Harbor Laboratory's Greg Hannon and Harvard University's Steve Elledge. It targets more than 30,000 genes with multiple shRNA constructs per gene and all protein classes, including those considered druggable.

The library began shipping on June 10, Open Biosystems said.

MultiCell Technologies said last week that it now offers HepLiu immortalized porcine hepatocytes and porcine media dry powder. MultiCell currently supplies immortalized non-tumorigenic human hepatocytes to the pharmaceutical industry.

MultiCell offers two versions of the porcine cells, HepLiu and eHepLiu. Both cell lines maintain significant basal levels of native liver functions and CYP inducibility, MultiCell said. The second-generation porcine line, eHepLiu, was enhanced by genetic selection and expresses nearly a 10X increase in basal CYP3A4 enzymatic activity, MultiCell said.

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.