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GenoSpectra, Genetix, Open Biosystems, MultiCell Technologies


GenoSpectra last week announced the launch of QuantiGene Plex, the first available multiplexed gene expression profiling assay based on Luminex's xMAP technology.

According to GenoSpectra, QuantiGene Plex allows accurate and precise quantification of multiple mRNA targets in a single well without the need for RNA purification, reverse transcription, or target amplification. It also can detect percent differences in expression, rather than fold differences measured by current technologies, GenoSpectra said.

Genetix last week announced the launch of CloneSelect, the company's mammalian cell-line management system, at the European Society for Animal Cell Technology in Harrogate, UK.

According to Genetix, CloneSelect is a microplate-based system that integrates confluence determination, expansion, stratification, and cherry picking with automated plate tracking and data management. The system incorporates a bar code reader for the tracking of source, replicate, and subsequent daughter plates. All data from CloneSelect is compatible with common LIMS systems, Genetix said.

Open Biosystems announced last week the completion of its ExpressionArrest whole genome human short hairpin library.

According to Open Biosystems, the shRNA library was developed by Cold Spring Harbor Laboratory's Greg Hannon and Harvard University's Steve Elledge. It targets more than 30,000 genes with multiple shRNA constructs per gene and all protein classes, including those considered druggable.

The library began shipping on June 10, Open Biosystems said.

MultiCell Technologies said last week that it now offers HepLiu immortalized porcine hepatocytes and porcine media dry powder. MultiCell currently supplies immortalized non-tumorigenic human hepatocytes to the pharmaceutical industry.

MultiCell offers two versions of the porcine cells, HepLiu and eHepLiu. Both cell lines maintain significant basal levels of native liver functions and CYP inducibility, MultiCell said. The second-generation porcine line, eHepLiu, was enhanced by genetic selection and expresses nearly a 10X increase in basal CYP3A4 enzymatic activity, MultiCell said.

The Scan

Could Cost Billions

NBC News reports that the new Alzheimer's disease drug from Biogen could cost Medicare in the US billions of dollars.

Not Quite Sent

The Biden Administration likely won't meet its goal of sending 80 million SARS-CoV-2 vaccine doses abroad by the end of the month, according to the Washington Post.

DTC Regulation Proposals

A new report calls on UK policymakers to review direct-to-consumer genetic testing regulations, the Independent reports.

PNAS Papers on Mosquito MicroRNAs, Acute Kidney Injury, Trichothiodystrophy

In PNAS this week: microRNAs involved in Aedes aegypti reproduction, proximal tubule cell response to kidney injury, and more.