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Genomatix s Kinase Knockdown Solutions and Multigenic Vectors and Carl Zeiss MicroImaging s LSM 5 Live and Axio Imager


Genomatix has announced the expansion of its kinase knockdown solutions to include custom multigenic vectors, the Roanoke, Va.-based company said last week. The kinase knockdown vectors can now be ordered with multiple transgenes integrated together as a single functional insert, the company said. Each multigenic vector is custom designed to cause the concurrent knockdown of specific kinases across a range of cellular micro-domains, Genomatix said.

Carl Zeiss MicroImaging has introduced the LSM 5 Live confocal microscope for live-cell imaging, as well as the Axio Imager modular microscope for fluorescence microscopy, the company said last week.

The LSM 5 Live allows real time observation of cellular motion and interaction by collecting up to 120 confocal images per second at a resolution of 512 pixels by 512 pixels, Zeiss said. The microscope features the new AnchroGate beam splitter for more efficient excitation efficiency and emission yield; an ultrafast Z-drive to acquire 3D image stacks every second; and traditional LSM 5 software combined with new software packages such as the Visual Macro Editor for automated workflow.

The Axio Imager is capable of widefield imaging, confocal microscopy, brightfield contrast techniques, phase contrast, and darkfield, the company said. It features new Infinity Contrast and Color-corrected System optics for maximum image contrast and quality while ensuring optimum transmission, contrast, and working distance in all techniques, Zeiss said.


The Scan

Guidelines for Ancient DNA Work

More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature.

And Cleared

A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times.

Suit Over Allegations

The Boston Globe reports that David Sabatini, who was placed on leave from MIT after allegations of sexual harassment, is suing his accuser, the Whitehead Institute, and the institute's director.

Nature Papers on Esophageal Cancer, Origin of Modern Horses, Exome Sequencing of UK Biobank Participants

In Nature this week: genetic and environmental influences of esophageal cancer, domestic horse origin traced to Western Eurasian steppes, and more.