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GeneFrontier, Abcellute, Artemis, Merck, Galapagos

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GeneFrontier to Distribute Abcellute’s Cell Lines in Japan
 
Abcellute and GeneFrontier have signed an exclusive agreement to manufacture, market, and distribute Abcellute’s preserved hepatocytes in Japan, the companies said last week.
 
Under the terms of the agreement, GeneFrontier is also allowed to establish sub-licenses with pharmaceutical or other companies to use the Abcellute technology internally, the companies said.
 
Financial details were not disclosed.
 
Abcellute was founded in 2001 as a spinout from Cardiff University in the UK. Its core technology allows researchers to preserve and store fresh primary hepatocytes for up to five days at non-freezing temperatures without the loss of biological function or principal biomarkers, the company said.
 

 
Artemis to Make Knock-Down Mice for Merck
 
Artemis Pharmaceuticals said last week that it has signed a deal to construct a “large number” of shRNA-engineered mouse models for use by Merck in in vivo functional analysis of select disease-related genes.
 
Under the deal, Artemis will create both constitutive and inducible knock-down mice using its proprietary vector construction, embryonic stem cell transfection, and inducible RNAi technologies. Merck will provide select shRNA sequences corresponding to mouse genes of interest.
 
Additional terms of the arrangement were not disclosed.
 

 
Galapagos Extends siRNA-Based Target-Validation Deal With Cystic Fibrosis Foundation
 
Galapagos has extended by 15 months and €800,000 ($1 million) a two-year agreement with Cystic Fibrosis Foundation Therapeutics to use its siRNA and cDNA collections to develop new treatments for cystic fibrosis, the company said last week.
 
Galapagos said its BioFocus DPI division is using its SilenceSelect adenoviral library to design assays that can identify and validate potential targets that could be the basis for the development of new medicines.
 
Galapagos signed the original two-year, €1.3-million research agreement with CFFT, a drug development affiliate of the Cystic Fibrosis Foundation, in April 2005.

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.