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Fisher, ForteBio, Acolyte, Berthold Tech

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Fisher's Pierce Unit Becomes NIH's 'Preferred Vendor' for Protein Profiling

The US National Institutes of Health has chosen Fisher Biosciences' Pierce Biotechnology unit to be its 'preferred vendor' for conducting protein sample analysis, Fisher said this week.

The NIH will use Pierce's SearchLight multiplex-profiling technology to analyze secreted protein expression in samples submitted by the NIH, including the National Cancer Institute, the National Institute of Allergies and Infectious Disease, and other affiliated NIH organizations, according to Fisher.

SearchLight is a multiplex sandwich enzyme-linked immunosorbent assay in a 96-well plate-based array format. Fisher claims it can measure up to 12 secreted proteins simultaneously per well.

Financial details of the arrangement were not discussed.


ForteBio Opens European Outpost in the Netherlands

ForteBio this week announced the opening of a sales and support office in the Netherlands.

ForteBio, based in Menlo Park, Calif., manufactures and markets label-free systems for detecting and analyzing molecular interactions. In particular, its flagship Octet System accelerates the characterization of antibody candidates by generating real-time quantitative and kinetic results, even in crude samples, the company said.

ForteBio said it opened to office to keep up with increased demand for the Octet in Europe. The Netherlands-based sales and support office will be locally managed by TouchDown Biomarketing.


Acolyte and Berthold Tech to Co-Market Cellular Enumeration Technology

Acolyte said this week that it has formed a marketing alliance with Berthold Technologies for its life science products.

Specifically, Berthold, based in Bad Wildbad, Germany, will distribute Acolyte's BacLite RapiTECT enumeration assays in Europe and the US. The BacLite range of products includes RapiTECT Gram Negative for the detection and enumeration of gram-negative bacterial cells; and BacLite RapiTECT Mammalian for mammalian cell enumeration.

Financial terms were not disclosed.

The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.