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Enzo Life Sciences and Cephalon Awarded US Patents

Enzo Life Sciences has been awarded US Patent 7,256,299, “Chemiluminescent reagents.”
The inventors listed on the patent are Jannis Stavrianopoulos and Elazar Rabbani.
This invention provides for labeling reagents, labeled targets, and processes for preparing labeling reagents, the abstract said. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes, or composite dyes. As stated in the abstract, these labeling reagents are useful for labeling probes or targets, including nucleic acids and proteins. These reagents can be usefully applied to protein and nucleic acid probe-based assays. They are also applicable to real-time detection processes.

Cephalon has been awarded US Patent 7,256,252, “Methods for detecting cell apoptosis.”
Inventors listed on the patent are Robert Siman, Donna Bozyczko-Coyne, and Sheryl Meyer.
The abstract said that the invention describes methods for the biochemical and immunohistochemical detection of cell apoptosis. The methods utilize the detection and measurement of polypeptide fragments generated during apoptosis. According to the abstract, conditions associated with apoptosis may be detected by the methods of this invention. Methods are also presented for the screening of potential therapeutic compounds which inhibit or stimulate apoptosis. Kits for detection of apoptosis and diagnosis of diseases are also provided.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.